Bis(2,2,2-trifluoroethyl) Ether - ≥99%(GC) , CAS No.333-36-8

CAS: 333-36-8 Cat. No.: B153017 Molecular Weight: 182.07 Beilstein Registry Number: 1811930 EC Number: 626-793-9

GRADE & PURITY ≥99%(GC)

Synonyms

Indoklon | Bis(2,2,2-trifluoroethyl) ether | 2,2,2-Trifluoroethyl ether | Flurotyl [INN] | Hexafluorodiethyl ether | SKF 6539 | Flurotyl | Bis(2,2,2-trifluoroethyl)ether | CAS-333-36-8 | Fluorothyl | Flurothyl | 1,1,1-Trifluoro-2-(2,2,2-trifluoroethoxy)et

Storage

Protected from light,Room temperature

Shipped In

Normal

Overview

Bis(2,2,2-trifluoroethyl) ether was used to diminish self-discharge of Li-S cells having both low- and high-sulfur-loading sulfur cathodes.

Specifications

Synonyms

Indoklon | Bis(2, 2, 2-trifluoroethyl) ether | 2, 2, 2-Trifluoroethyl ether | Flurotyl [INN] | Hexafluorodiethyl ether | SKF 6539 | Flurotyl | Bis(2, 2, 2-trifluoroethyl)ether | CAS-333-36-8 | Fluorothyl | Flurothyl | 1, 1, 1-Trifluoro-2-(2, 2, 2-trifluoroethoxy)et

Specifications & Purity

≥99%(GC)

Storage

Protected from light, Room temperature

Shipped In

Normal

Purity

≥99%(GC)

Names and Identifiers

• Pubchem Sid: 504751840
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504751840
• Canonical Smiles: C(C(F)(F)F)OCC(F)(F)F
• IUPAC Name: 1,1,1-trifluoro-2-(2,2,2-trifluoroethoxy)ethane
• InChIKey: KGPPDNUWZNWPSI-UHFFFAOYSA-N
• INCHI: 1S/C4H4F6O/c5-3(6,7)1-11-2-4(8,9)10/h1-2H2
• Isomeric SMILES: C(C(F)(F)F)OCC(F)(F)F
• WGK Germany: 3
• RTECS: KN3675000
• Molecular Weight: 182.07
• Beilstein: 1811930
• Reaxy-Rn: 1811927
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1811927&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Class Organooxygen compounds
      • Subclass Ethers

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Class: Organooxygen compounds
• Subclass: Ethers
• Intermediate Tree Nodes: Not available
• Direct Parent: Dialkyl ethers
• Alternative Parents: Organofluorides Hydrocarbon derivatives Alkyl fluorides
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Dialkyl ether - Hydrocarbon derivative - Organofluoride - Organohalogen compound - Alkyl halide - Alkyl fluoride - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as dialkyl ethers. These are organic compounds containing the dialkyl ether functional group, with the formula ROR', where R and R' are alkyl groups.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Chemical and Physical Properties

• Sensitivity: Light sensitive；Moisture sensitive
• Refractive Index: 1.28
• Flash Point(°F): 33.8 °F
• Flash Point(°C): 1°C
• Boil Point(°C): 64°C
• Molecular Weight: 182.060 g/mol
• XLogP3: 2.300
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 2
• Exact Mass: 182.017 Da
• Monoisotopic Mass: 182.017 Da
• Topological Polar Surface Area: 9.200 Ų
• Heavy Atom Count: 11
• Formal Charge: 0
• Complexity: 98.700
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Wang Hansen, Yan Xiaolin, Zhang Rupeng, Sun Juanjuan, Feng Fuxiang, Li Haoran, Liang Jinding, Wang Yuchun, Ye Guangzhou, Luo Xiaonan, Huang Shengyuan, Wan Pan, Hung Samantha T., Ye Fangjun, Chen Fangyun, Wu Erxiao, Zhou Jinfei, Ulissi Ulderico, Ge Xiaoming, Liu Chengyong, Xu Bo, Liu Na, Ouyang Chuying.  (2025)  Application-driven design of non-aqueous electrolyte solutions through quantification of interfacial reactions in lithium metal batteries.  Nature Nanotechnology,      [PMID:40437200] [10.1038/s41565-025-01935-y]