BMX-IN-1 - Moligand™, 10 mM in DMSO , CAS No.1431525-23-3
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SKU
B1499255
BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys 496 in the BMX ATP binding domain with an IC 50 of 8 nM, also targets the related Bruton’s tyrosine kinase ( BTK ) with an IC 50 value of 10.4 nM, but is more than 47-656-fold less potent against Blk , JAK3 , EGFR , Itk , or Tec activity.
Más Información
| CAS | 1431525-23-3 |
|---|---|
| Concentración | 10 mM in DMSO |
| Especificaciones y pureza | Moligand™, 10 mM in DMSO |
| Condiciones de almacenamiento de almacenamiento | Store at -80°C |
| Enviado en | Dry ice packs + Cold packs |
| Product Description | BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys 496 in the BMX ATP binding domain with an IC 50 of 8 nM, also targets the related Bruton’s tyrosine kinase ( BTK ) with an IC 50 value of 10.4 nM, but is more than 47-656-fold less potent against Blk , JAK3 , EGFR , Itk , or Tec activity. |
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