BOC-D-Glu-OH - BioReactivo , CAS No.34404-28-9

CAS: 34404-28-9 Cat. No.: B117166 Fórmula: C₁₀H₁₇NO₆ Peso molecular: 247.2 Número EC: 837-676-9

GRADE & PURITY BioReagent

Synonyms

A847898 | SCHEMBL1318658 | Q-101678 | AQTUACKQXJNHFQ-ZCFIWIBFSA-N | HY-W039449 | AC-24111 | N-(tert-Butoxycarbonyl)-D-glutamic Acid | (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanedioic acid | Boc-L-Glu-OH | AC-24109 | Boc-D-Glu-OH | MFCD00190790 |

Storage

Room temperature

Shipped In

Normal

Specifications

Sinónimos

A847898 | SCHEMBL1318658 | Q-101678 | AQTUACKQXJNHFQ-ZCFIWIBFSA-N | HY-W039449 | AC-24111 | N-(tert-Butoxycarbonyl)-D-glutamic Acid | (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanedioic acid | Boc-L-Glu-OH | AC-24109 | Boc-D-Glu-OH | MFCD00190790 |

Especificaciones y pureza

BioReactivo

Condiciones de almacenamiento de almacenamiento

Room temperature

Enviado en

Normal

Grado

BioReagent

Nombres e identificadores

• Pubchem Sid: 488196103
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488196103
• Sonrisas canónicas: CC(C)(C)OC(=O)NC(CCC(=O)O)C(=O)O
• IUPAC Name: (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanedioic acid
• InChIKey: AQTUACKQXJNHFQ-ZCFIWIBFSA-N
• INCHI: 1S/C10H17NO6/c1-10(2,3)17-9(16)11-6(8(14)15)4-5-7(12)13/h6H,4-5H2,1-3H3,(H,11,16)(H,12,13)(H,14,15)/t6-/m1/s1
• Isómeros SMILES: CC(C)(C)OC(=O)N[C@H](CCC(=O)O)C(=O)O
• Peso molecular: 247.2
• Reaxy-Rn: 2418562
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2418562&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Glutamic acid and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: Glutamic acid and derivatives
• Alternative Parents: Branched fatty acids Dicarboxylic acids and derivatives Carbamate esters Organic carbonic acids and derivatives Carboxylic acids Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Glutamic acid or derivatives - Branched fatty acid - Dicarboxylic acid or derivatives - Fatty acid - Fatty acyl - Carbamic acid ester - Carbonic acid derivative - Carboxylic acid - Hydrocarbon derivative - Carbonyl group - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic oxide - Organopnictogen compound - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as glutamic acid and derivatives. These are compounds containing glutamic acid or a derivative thereof resulting from reaction of glutamic acid at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Soluble in Dichloromethane, Ether, Ethyl Acetate and Methanol；Dissolved in water
• Rotación específica [α]: 14 ° (C=1, MeOH)
• Punto de fusión (°C): 108 °C(dec.)
• Peso molecular: 247.240 g/mol
• XLogP3: 0.400
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 7
• Exact Mass: 247.106 Da
• Monoisotopic Mass: 247.106 Da
• Topological Polar Surface Area: 113.000 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 306.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

1. Hai Xiao, Shuqin Han, Huricha Baigude.  (2021)  Regulation of microglia polarization via mannose receptor-mediated delivery of siRNA by ligand-functionalized DoGo LNP.  RSC Advances,  11  (52): (32549-32558).  [PMID:35493551] [10.1039/D1RA04293A]

2. Tsogzolmaa Ganbold, Gerile Gerile, Hai Xiao, Huricha Baigude.  (2017)  Efficient in vivo siRNA delivery by stabilized D-peptide-based lipid nanoparticles.  RSC Advances,  7  (15): (8823-8831).  [PMID:] [10.1039/C6RA25862J]

3. Liping Li, Qiuxia Zhang, Hong Huo, Jianjun Zhou, Lin Li.  (2016)  Glutamic acid derivatives as gelators for electrolyte of lithium ion batteries.  RSC Advances,  6  (91): (88820-88825).  [PMID:] [10.1039/C6RA18638F]

4. Hai Xiao, Altanzul Altangerel, Gerile Gerile, Yinga Wu, Huricha Baigude.  (2016)  Design of Highly Potent Lipid-Functionalized Peptidomimetics for Efficient in Vivo siRNA Delivery.  ACS Applied Materials & Interfaces,      [PMID:26964858] [10.1021/acsami.5b12144]