Burimamide oxalate - Moligand™ , Agonist of H 2 receptor;Antagonist of H 2 receptor;Antagonist of H 3 receptor;Antagonist of H 4 receptor, CAS No.34970-69-9, Agonist of H 2 receptor;Antagonist of H 2 receptor;Antagonist of H 3 receptor;Antagonist of H 4 receptor

CAS: 34970-69-9 Cat. No.: B339433 Fórmula: C9H16N4S•C2H2O4 Peso molecular: 302.35
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
Synonyms
N-(4-imidazol-4-ylbutyl)-N'-methylthiourea | UNII-TN5A4OD2TV | BDBM22888 | CHEBI:3221 | DTXSID00188519 | N-methyl-N'-[4-(4-imidazolyl)butyl]thiourea | N-METHYL-N'-(4(5)-IMIDAZOLYLBUTYL)THIOUREA | PDSP2_001081 | PDSP1_001097 | BDBM50483128 | Q3268750 | THI
Storage
Store at 2-8°C,Desiccated
Shipped In
Wet ice
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Size
Alemania (EU)
USA*
Price
Qty
2.5mg
B339433-2.5mg
Fabricado bajo pedido · 8–12 semanas
286,27€
10mg
B339433-10mg
Fabricado bajo pedido · 8–12 semanas
822,53€
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™ Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at 2-8°C,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Burimamide oxalate is a mixed Histamine H|3|Receptor and Histamine H|2|Receptor(H|2|/H|3|) antagonist. In SK-N-MC cells, this compound displays partial agonist activity. Burimamide oxalate also produces antinicoceptive effects.

Specifications

Sinónimos
N-(4-imidazol-4-ylbutyl)-N'-methylthiourea | UNII-TN5A4OD2TV | BDBM22888 | CHEBI:3221 | DTXSID00188519 | N-methyl-N'-[4-(4-imidazolyl)butyl]thiourea | N-METHYL-N'-(4(5)-IMIDAZOLYLBUTYL)THIOUREA | PDSP2_001081 | PDSP1_001097 | BDBM50483128 | Q3268750 | THI
Especificaciones y pureza
Moligand™
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C,Desiccated
Enviado en
Wet ice
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
AGONIST, ANTAGONIST
Mecanismo de acción
Agonist of H 2 receptor;Antagonist of H 2 receptor;Antagonist of H 3 receptor;Antagonist of H 4 receptor
Propiedades del producto
Datos Ki
Histamine H4 Receptor: Ki= 39.81 nM (human); Histamine H3 Receptor: Ki= 70 nM; Histamine H1 Receptor: Ki= 290 μM; Histamine H2 Receptor: Ki= 3.98 μM (human)
Nombres e identificadores
Sonrisas canónicas
CNC(=S)NCCCCC1=CN=CN1
IUPAC Name
1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea
InChIKey
HXRBAVXGYZUSED-UHFFFAOYSA-N
INCHI
1S/C9H16N4S/c1-10-9(14)12-5-3-2-4-8-6-11-7-13-8/h6-7H,2-5H2,1H3,(H,11,13)(H2,10,12,14)
Isómeros SMILES
CNC(=S)NCCCCC1=CN=CN1
Peso molecular
302.35
Reaxy-Rn
24207621
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24207621&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClaseAzoles
SubclassImidazoles
Intermediate Tree Nodes Not available
Direct ParentImidazoles
Alternative Parents Heteroaromatic compounds  Thioureas  Azacyclic compounds  Organopnictogen compounds  Organonitrogen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Heteroaromatic compound - Imidazole - Thiourea - Azacycle - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organosulfur compound - Organonitrogen compound - Aromatic heteromonocyclic compound
DescripciónThis compound belongs to the class of organic compounds known as imidazoles. These are compounds containing an imidazole ring, which is an aromatic five-member ring with two nitrogen atoms at positions 1 and 3, and three carbon atoms.
External Descriptors imidazoles
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
HRH4 Tchem Histamine H4 receptor (4 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HRH3 Tclin Histamine H3 receptor (4 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HRH2 Tclin Histamine H2 receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HRH2 Tclin Histamine H2 receptor (5428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH3 Tclin Histamine H3 receptor (10389 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Hrh4 Histamine H4 receptor (388 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
fba Putative fructose-1,6-bisphosphate aldolase (15559 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
SolubilidadSoluble in water (100 mM), and DMSO (100 mM).
Índice de refracciónn20D1.59 (Predicted)
Peso molecular212.320 g/mol
XLogP30.400
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count2
Rotatable Bond Count5
Exact Mass212.11 Da
Monoisotopic Mass212.11 Da
Topological Polar Surface Area84.800 Ų
Heavy Atom Count14
Formal Charge0
Complexity174.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculadoras de soluciones
Reseñas

Reseñas de cliente

Preguntas frecuentes

What are the CAS number, molecular formula and molecular weight?
The CAS Number is 34970-69-9, the molecular formula is C9H16N4S?C2H2O4, and the molecular weight is 302.35 g/mol. InChIKey HXRBAVXGYZUSED-UHFFFAOYSA-N.
What is Moligand??
Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.
How should this product be stored?
Store at 2–8 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.
How is this product shipped?
This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

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