Carbazole - ≥96% , CAS No.86-74-8

CAS: 86-74-8 Cat. No.: C104875 Fórmula: C₁₂H₉N Peso molecular: 167.21 Beilstein Registry Number: 3956 Número EC: 201-696-0

CALIDAD & PUREZA ≥96%

Synonyms

9-H-carbazole | 9H-Carbazole | C3722 | Dibenzo(b,d)pyrrole | CAS-86-74-8 | HSDB 2164 | DTXSID4020248 | para-carbazole | NCGC00256533-01 | 9-Azafluorene | Chlorophenesin carbamate | NSC3498 | NSC-3498 | Carbazole, >=95% (GC) | CCRIS 121 | CARBAZOLE | Carba

Storage

Room temperature

Shipped In

FedEx DG Service

Descripción general

Carbazole is an aromatic heterocyclic organic molecule. It mainly interacts with DNA and damages it. These events suppress the synthesis of new DNA or RNA. Carbazole derivatives are involved in antimicrobial, antitumor, antiepileptic, antihistaminic, antioxidant, anti-inflammatory, antidiarrhoeal, analgesic, neuroprotective and pancreatic lipase suppression activities.
Carbazole has been used in the uronic acid assay

Especificaciones

Sinónimos

9-H-carbazole | 9H-Carbazole | C3722 | Dibenzo(b,d)pyrrole | CAS-86-74-8 | HSDB 2164 | DTXSID4020248 | para-carbazole | NCGC00256533-01 | 9-Azafluorene | Chlorophenesin carbamate | NSC3498 | NSC-3498 | Carbazole, >=95% (GC) | CCRIS 121 | CARBAZOLE | Carba

Especificaciones y pureza

≥96%

Condiciones de almacenamiento de almacenamiento

Room temperature

Enviado en

FedEx DG Service

Pureza

≥96%

Nombres e identificadores

Pubchem Sid

488180177

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488180177

Sonrisas canónicas

C1=CC=C2C(=C1)C3=CC=CC=C3N2

IUPAC Name

9H-carbazole

InChIKey

UJOBWOGCFQCDNV-UHFFFAOYSA-N

INCHI

1S/C12H9N/c1-3-7-11-9(5-1)10-6-2-4-8-12(10)13-11/h1-8,13H

Isómeros SMILES

C1=CC=C2C(=C1)C3=CC=CC=C3N2

WGK Alemania

2

RTECS

FE3150000

Número ONU

3077

Grupo de embalaje

III

Peso molecular

167.21

Beilstein

3956

Reaxy-Rn

3956

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3956&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Indoles and derivatives
      • Subclass Carbazoles

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Indoles and derivatives
• Subclass: Carbazoles
• Intermediate Tree Nodes: Not available
• Direct Parent: Carbazoles
• Alternative Parents: Indoles Benzenoids Pyrroles Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Carbazole - Indole - Benzenoid - Heteroaromatic compound - Pyrrole - Azacycle - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as carbazoles. These are compounds containing a three ring system containing a pyrrole ring fused on either side to a benzene ring.
• External Descriptors: a carbazole

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

AR Tclin Androgen Receptor (11781 Activities)

Discover Target: AR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TYR Tclin Tyrosinase (717 Activities)

Discover Target: TYR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTH1R Tclin Parathyroid hormone receptor (47172 Activities)

Discover Target: PTH1R

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

Discover Target: ALDH1A1

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U-937 (7138 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KIF11 Tchem Kinesin-like protein 1 (1720 Activities)

Discover Target: KIF11

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)

Discover Target: HSD17B10

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Objetivos asociados (no humanos)

Staphylococcus aureus (210822 Activities)

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Bovine viral diarrhea virus 1 (1277 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rorc Nuclear receptor ROR-gamma (89407 Activities)

Discover Target: Rorc

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

clpP ATP-dependent Clp protease proteolytic subunit (245 Activities)

Discover Target: clpP

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: It is insoluble in water;Solubility in hot EtOH:almost transparency
• Punto de inflamación (°F): 428℉
• Punto de inflamación (°C): 220°C
• Punto de ebullición (°C): 355°C
• Punto de fusión (°C): 245°C
• Peso molecular: 167.210 g/mol
• XLogP3: 3.700
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 167.073 Da
• Monoisotopic Mass: 167.073 Da
• Topological Polar Surface Area: 15.800 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 170.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1