Carbidopa - Moligand™, 10mM in DMSO , Inhibitor of L-Aromatic amino-acid decarboxylase , CAS No.28860-95-9, Inhibitor of L-Aromatic amino-acid decarboxylase

CAS: 28860-95-9 Cat. No.: C408039 Molecular Weight: 226.23 EC Number: 249-271-9
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
Synonyms
(αS)​-α-​hydrazinyl-​3,​4-​dihydroxy-​α-​methyl-​benzenepropanoic acid
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1ml
C408039-1ml
2

$141.90

$205.90
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Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Information

Carbidopa Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor with an IC50 of 29 ± 2 μM.
In vitro


In vivo


Cell Data

cell lines:Breast cancer cell lines including SW620 colon, A2780 ovarian, HCC1937, Hs578T, MDA-MB-231, MDA-MB-436, and T47D

Concentrations:

Incubation Time:

Powder Purity:≥99%

Specifications

Synonyms
(αS)​-α-​hydrazinyl-​3, ​4-​dihydroxy-​α-​methyl-​benzenepropanoic acid
Specifications & Purity
Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms
Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor with an IC50 of 29 ± 2 μM.
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
INHIBITOR
Mechanism of action
Inhibitor of L-Aromatic amino-acid decarboxylase
Names and Identifiers
Isomeric SMILES C[C@](CC1=CC(=C(C=C1)O)O)(C(=O)O)NN
WGK Germany 3
Alternate CAS 38821-49-7
Molecular Weight 226.23
Reaxy-Rn 657532
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=657532&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
DDC Tclin Aromatic-L-amino-acid decarboxylase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SolubilitySolubility (25°C) In vitro      
Citations of This Product
References
1. Jin Yuan Zhang, Ying Zhang, Yu Zou, Ze Li Bo Xu, Bo Zhang, Wang Ren.  (2023)  Physicochemically modulated fluorescence-scattering ratiometric sensor for selective and visual detection of levodopa.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:38091648] [10.1016/j.saa.2023.123746]
2. Da-Wei Zhou, Meng Yin, Yun Shen, Xiao-Xue Wang, Chen-Yu Wang, Ke-Zheng Chen, Qi Fang, Sheng-Lin Qiao.  (2024)  LDHzyme-assisted high-performance on-site tracking of levodopa pharmacokinetics for Parkinson's disease management.  BIOSENSORS & BIOELECTRONICS,      [PMID:39536419] [10.1016/j.bios.2024.116926]
3. Shanying Han, Tianyu Du, Hui Jiang, Xuemei Wang.  (2016)  Synergistic effect of pyrroloquinoline quinone and graphene nano-interface for facile fabrication of sensitive NADH biosensor.  BIOSENSORS & BIOELECTRONICS,      [PMID:27156055] [10.1016/j.bios.2016.04.092]
Solution Calculators
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