Carboplatin - Moligand™, ≥99.95% metals basis , CAS No.41575-94-4

CAS: 41575-94-4 Cat. No.: C295384 Fórmula: C₆H₁₂N₂O₄Pt Peso molecular: 371.25 Número EC: 255-446-0

GRADE & PURITY Moligand™, ≥99.95% metals basis

Synonyms

AB01273939-01 | EN300-123065 | NSC758182 | NSC-758182 | STL451040 | Tox21_112586_1 | Carboplatinum | DTXCID201476080 | Amikacin impurity I, European Pharmacopoeia (EP) Reference Standard | Pharmakon1600-01502106 | SCHEMBL4964 | Lopac0_000230 | NSC201345 |

Storage

Store at 2-8°C,Protected from light

Shipped In

Wet ice

Descripción general

Carboplatin is believed to form inter- and intrastrand DNA adducts which activate signaling pathways culminating in apoptosis. The development of carboplatin was inspired from the efficacy of its progenitor, Cisplatin (sc-200896), the first of this class of antineoplastic agents. The action of this group of platinum-based compounds is primarily attributed to DNA adduct formation, however, these molecules also bind other biological molecules, including enzymes, which might play a role in their mechanism of action.
An antitumor agent that binds to DNA leading to apoptosis

Product class
hAPIs, Metal based hAPIs

Chemical properties

Chemical formula

C6H12N2O4Pt

Empirical formula

[Pt(NH3)2(cbdc)]

Molecular weight

371.25

Metal

Pt

Theoretical metal content

53

Physical state

powder

Color
Metal purity

white

99.95

Specifications

Sinónimos

AB01273939-01 | EN300-123065 | NSC758182 | NSC-758182 | STL451040 | Tox21_112586_1 | Carboplatinum | DTXCID201476080 | Amikacin impurity I, European Pharmacopoeia (EP) Reference Standard | Pharmakon1600-01502106 | SCHEMBL4964 | Lopac0_000230 | NSC201345 |

Especificaciones y pureza

Moligand™, ≥99.95% metals basis

Mecanismos bioquímicos y fisiológicos

Carboplatin damages DNA by forming intrastrand cross-links with neighboring guanine residues. Tumors acquire resistance to these drugs through the loss of DNA-mismatch repair (MMR) activity and the resultant decrease in the induction of programmed cell de

Información jurídica

Product of Umicore

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C,Protected from light

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Pureza

≥99.95% metals basis

Nombres e identificadores

Pubchem Sid

504758672

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504758672

Sonrisas canónicas

C1CC(C1)(C(=O)O)C(=O)O.[NH2-].[NH2-].[Pt+2]

IUPAC Name

azanide;cyclobutane-1,1-dicarboxylic acid;platinum(2+)

InChIKey

VSRXQHXAPYXROS-UHFFFAOYSA-N

INCHI

1S/C6H8O4.2H2N.Pt/c7-4(8)6(5(9)10)2-1-3-6;;;/h1-3H2,(H,7,8)(H,9,10);2*1H2;/q;2*-1;+2

Isómeros SMILES

C1CC(C1)(C(=O)O)C(=O)O.[NH2-].[NH2-].[Pt+2]

WGK Alemania

3

RTECS

TP2300000

CAS alternativo

41575-94-4

Número NSC

201345

Términos de entrada MeSH

Blastocarb;Carboplat;Carboplatin;Carbosin;Carbotec;CBDCA;cis-Diammine(cyclobutanedicarboxylato)platinum II;Ercar;JM 8;JM-8;JM8;Nealorin;Neocarbo;NSC 241240;NSC-241240;NSC241240;Paraplatin;Paraplatine;Platinwas;Ribocarbo

Peso molecular

371.25

Reaxy-Rn

25079300

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25079300&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboxylic acids and derivatives
      • Subclass Dicarboxylic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboxylic acids and derivatives
• Subclass: Dicarboxylic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Dicarboxylic acids and derivatives
• Alternative Parents: Organic transition metal salts Carboxylic acids Organic oxides Organic nitrogen compounds Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic homomonocyclic compounds
• Substituents: Dicarboxylic acid or derivatives - Organic transition metal salt - Carboxylic acid - Organic nitrogen compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organic salt - Organooxygen compound - Carbonyl group - Aliphatic homomonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid groups.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Soluble in water.
• Sensibilidad: Light sensitive.
• Punto de fusión (°C): >275℃
• Peso molecular: 371.250 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 0
• Exact Mass: 371.045 Da
• Monoisotopic Mass: 371.045 Da
• Topological Polar Surface Area: 76.600 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 177.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 4

XLogP3

Preguntas frecuentes

What does the trace-metals specification mean?

This product is specified at ≥99.95% on a trace-metals basis. That figure describes metallic impurity content rather than overall chemical assay, so it is the relevant specification for ICP-MS, semiconductor and battery applications. Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at 2–8 °C, protected from light. The material is light-sensitive — keep it in its original opaque or amber container.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 41575-94-4, the molecular formula is C6H12N2O4Pt, and the molecular weight is 371.25 g/mol. InChIKey VSRXQHXAPYXROS-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.