CH-0793076 TFA - ≥98% , CAS No.C659020

CAS: C659020 Cat. No.: C659020 Fórmula: C₂₈H₂₇F₃N₄O₆ Peso molecular: 572.53

CALIDAD & PUREZA ≥98%

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

Descripción general

CH-0793076 (TP3076) TFA, a hexacyclic camptothecin analog, is active drug and major metabolite of TP300. CH-0793076 TFA inhibits DNA topoisomerase I with an IC 50 of 2.3 μM. CH-0793076 TFA is efficacious against cells expressing BCRP (breast cancer resist

Appearance:Solid

IC50& Target:Topoisomerase I 2.3 μM (IC 50 )

In Vitro:CH0793076 (TP3076) TFA (6 days at 37°C) shows antiproliferative activity against PC-6/BCRP and PC-6/pRC cells, with IC 50 s of 0.35 and 0.18 nM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference o

Biological Activity:CH-0793076 (TP3076) TFA, a hexacyclic camptothecin analog, is active drug and major metabolite of TP300. CH-0793076 TFA inhibits DNA topoisomerase I with an IC 50 of 2.3 μM. CH-0793076 TFA is efficacious against cells expressing BCRP (breast cancer resist

Especificaciones

Especificaciones y pureza

≥98%

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C,Desiccated

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Pureza

≥98%

Nombres e identificadores

Peso molecular

572.53

Propiedades químicas y físicas

• Solubilidad: DMSO : 30 mg/mL (52.40 mM; Need ultrasonic)