Cilofexor - Moligand™, 10 mM in DMSO , CAS No.1418274-28-8

CAS: 1418274-28-8 Cat. No.: C1494248 Molecular Weight: 586.85 EC Number: 890-395-3 PubChem CID: 71228883

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Cilofexor (GS-9674) is a potent, selective and orally active nonsteroidal FXR agonist with an EC 50 of 43 nM. Cilofexor has anti-inflammatory and antifibrotic effects. Cilofexor has the potential for primary sclerosing cholangitis (PSC) and nonalcoholic steatohepatitis (NASH) research .

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

AGONIST

Product Properties

• ALogP: 5.3

Names and Identifiers

• Isomeric SMILES: C1CC1C2=C(C(=NO2)C3=C(C=CC=C3Cl)Cl)COC4=CC(=C(C=C4)C5(CN(C5)C6=NC=CC(=C6)C(=O)O)O)Cl
• Alternate CAS: 1418274-28-8,2163097-55-8
• PubChem CID: 71228883
• MeSH Entry Terms: 2-(3-(2-Chloro-4-((5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl)methoxy)phenyl)-3-hydroxy-1-azetidinyl)isonicotinic acid;2-(3-(2-chloro-4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)phenyl)-3-hydroxyazetidin-1-yl)isonicotinic acid
• Molecular Weight: 586.85