Coelenterazine - ≥94% , CAS No.55779-48-1

CAS: 55779-48-1 Cat. No.: C131248 Fórmula: C₂₆H₂₁N₃O₃ Peso molecular: 423.46 Número EC: 637-236-4

CALIDAD & PUREZA ≥94%

Synonyms

COELENTERAZINE LUCIFERIN | LUCIFERIN (OPLOPHORUS) | Coelenterazine, native, solid | BCP15542 | C-7002 | 6-(4-HYDROXYPHENYL)-2-((4-HYDROXYPHENYL)METHYL)-8-(PHENYLMETHYL)IMIDAZO(1,2-A)PYRAZIN-3(7H)-ONE | 8-benzyl-6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)meth

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Descripción general

A bioluminescence probe for measuring Ca²⁺ concentration in cells with a high sensitivity and large dynamic range

Especificaciones

Sinónimos

COELENTERAZINE LUCIFERIN | LUCIFERIN (OPLOPHORUS) | Coelenterazine, native, solid | BCP15542 | C-7002 | 6-(4-HYDROXYPHENYL)-2-((4-HYDROXYPHENYL)METHYL)-8-(PHENYLMETHYL)IMIDAZO(1,2-A)PYRAZIN-3(7H)-ONE | 8-benzyl-6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)meth

Especificaciones y pureza

≥94%

Mecanismos bioquímicos y fisiológicos

When Ca 2+is combined with the complex, the luminescent group of jellyfish luminescent protein complex is oxidized by oxygen and emits light at 465 nm; It is used to measure intracellular Ca 2+concentration with high sensitivity and large dynamic range.

Condiciones de almacenamiento de almacenamiento

Protected from light,Store at -20°C,Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥94%

Nombres e identificadores

Pubchem Sid

488202912

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488202912

Sonrisas canónicas

C1=CC=C(C=C1)CC2=NC(=CN3C2=NC(=C3O)CC4=CC=C(C=C4)O)C5=CC=C(C=C5)O

IUPAC Name

8-benzyl-6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]imidazo[1,2-a]pyrazin-3-ol

InChIKey

LNCOEGVEEQDKGX-UHFFFAOYSA-N

INCHI

1S/C26H21N3O3/c30-20-10-6-18(7-11-20)15-23-26(32)29-16-24(19-8-12-21(31)13-9-19)27-22(25(29)28-23)14-17-4-2-1-3-5-17/h1-13,16,30-32H,14-15H2

Isómeros SMILES

C1=CC=C(C=C1)CC2=NC(=CN3C2=NC(=C3O)CC4=CC=C(C=C4)O)C5=CC=C(C=C5)O

Peso molecular

423.46

Reaxy-Rn

37031400

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=37031400&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Imidazopyrazines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Imidazopyrazines
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Imidazopyrazines
• Alternative Parents: 1-hydroxy-2-unsubstituted benzenoids Pyrazines N-substituted imidazoles Benzene and substituted derivatives Heteroaromatic compounds Azacyclic compounds Organooxygen compounds Organonitrogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Imidazopyrazine - Phenol - 1-hydroxy-2-unsubstituted benzenoid - Monocyclic benzene moiety - N-substituted imidazole - Pyrazine - Benzenoid - Azole - Imidazole - Heteroaromatic compound - Azacycle - Organic oxygen compound - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as imidazopyrazines. These are organic heteropolycyclic compounds containing a pyrazine ring fused to an imidazole ring. These also include hydrogenated derivatives of the imidazopyrazine moiety. Imidazole is 5-membered ring consisting of three carbon atoms, and two nitrogen centers at the 1- and 3-positions. Pyrazine is a 6-membered ring consisting of six carbon atoms and two nitrogen centers at ring positions 1 and 4.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

ABCB1 Tchem Multidrug resistance protein 1 (1 Activities)

Discover Target: ABCB1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Propiedades químicas y físicas

• Sensibilidad: Sensitive to light; sensitive to humidity
• Peso molecular: 423.500 g/mol
• XLogP3: 5.500
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 423.158 Da
• Monoisotopic Mass: 423.158 Da
• Topological Polar Surface Area: 90.900 Ų
• Heavy Atom Count: 32
• Formal Charge: 0
• Complexity: 585.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1