CORM-401 - 10mM in DMSO , CAS No.1001015-18-4

CAS: 1001015-18-4 Cat. No.: C655257 Fórmula: C₈H₆MnNO₆S₂ Peso molecular: 331.20

CALIDAD & PUREZA 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

CORM-401 is an oxidant-sensitive CO-releasing molecule. CORM-401 induces NO increase in the regulation of endothelial calcium signalling. CORM-401 reduces TNF-α/CHX and H2O2-induced ROS production. CORM-401 uncouples mitochondrial respiration and inhibits glycolysis .

In Vitro

CORM-401 (100 µM; 1h) induces the NO production in endothelial EA.hy926 cells. CORM-401 (30 µM) induces peak-like calcium signal and augmentes coupling of endoplasmic reticulum and plasmalemmal store-operated calcium channels. CORM-401 (50 µM; 1h) significantly reduces TNF-α/CHX and H2O2-induced ROS production and cell death. CORM-401 (0.5, 1 mM) induces a persistent increase in the oxygen consumption rate in endothelial EA.hy926 cells. CORM-401 (10, 30, 100 µM) induces a concentration-dependent increase in OCR and a simultaneous decrease in ECAR. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Especificaciones

Especificaciones y pureza

10mM in DMSO

Mecanismos bioquímicos y fisiológicos

CORM-401 is an oxidant-sensitive CO-releasing molecule. CORM-401 induces NO increase in the regulation of endothelial calcium signalling. CORM-401 reduces TNF-α/CHX and H2O2-induced ROS production. CORM-401 uncouples mitochondrial respiration and inhibits

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

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Tipo de acción

INHIBITOR

Nombres e identificadores

Peso molecular

331.20

Preguntas frecuentes

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1001015-18-4, the molecular formula is C8H6MnNO6S2, and the molecular weight is 331.20 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.