Name: Cromakalim - Moligand™, ≥99% , Activator of K ir6.1;Activator of K ir6.2;Channel blocker of K v1.7;Channel blocker of K v3.1, CAS No.94470-67-4, Activator of K ir6.1;Activator of K ir6.2;Channel blocker of K v1.7;Channel blocker of K v3.1
SKU: C274992
Availability: InStock

Cromakalim - Moligand™, ≥99% , Activator of K ir6.1;Activator of K ir6.2;Channel blocker of K v1.7;Channel blocker of K v3.1, CAS No.94470-67-4, Activator of K ir6.1;Activator of K ir6.2;Channel blocker of K v1.7;Channel blocker of K v3.1

CAS: 94470-67-4 Cat. No.: C274992 Fórmula: C₁₆H₁₈N₂O₃ Peso molecular: 286.33

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Cromakalim - Moligand™, ≥99% CAS No(94470-67-4) by Aladdin Scientific

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Disponible para pedir

GRADE & PURITY Moligand™ ? ≥99%

Synonyms

Storage

Conservar a 2-8°C,Desecado

Shipped In

Hielo húmedo

Descripción general Specifications Nombres e identificadores Documentation Advanced Data Taxonomic Classification Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Calculadoras de soluciones Reseñas

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Why this grade

Moligand™, ≥99% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Conservar a 2-8°C,Desecado Ships Hielo húmedo Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Almacenar a +4°C. Almacenar en condiciones de desecación. El producto puede almacenarse hasta 12 meses.

Specifications

Sinónimos

Especificaciones y pureza

Moligand™, ≥99%

Mecanismos bioquímicos y fisiológicos

Activador del canal K IR 6.x (K ATP ). Potente relajante del músculo liso, activo por vía oral.

Condiciones de almacenamiento de almacenamiento

Conservar a 2-8°C,Desecado

Enviado en

Hielo húmedo

Grado

Moligand™

Tipo de acción

ACTIVATOR, CHANNEL BLOCKER

Mecanismo de acción

Activator of K ir6.1;Activator of K ir6.2;Channel blocker of K v1.7;Channel blocker of K v3.1

Nota

Siempre que sea posible, prepare y utilice las soluciones el mismo día. Sin embargo, si necesita preparar soluciones madre con antelación, le recomendamos que almacene la solución como alícuotas en viales herméticamente cerrados a -20°C. Por lo general, podrán utilizarse durante un mes. Antes de su uso, y antes de abrir el vial, le recomendamos que deje que el producto se equilibre a temperatura ambiente durante al menos 1 hora. ¿Necesita más consejos sobre solubilidad, uso y manipulación? Visite nuestra página de preguntas frecuentes (FAQ) para obtener más información.

Pureza

≥99%

Nombres e identificadores

Sonrisas canónicas

CC1(C(C(C2=C(O1)C=CC(=C2)C#N)N3CCCC3=O)O)C

IUPAC Name

3-hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-3,4-dihydrochromene-6-carbonitrile

InChIKey

TVZCRIROJQEVOT-UHFFFAOYSA-N

INCHI

1S/C16H18N2O3/c1-16(2)15(20)14(18-7-3-4-13(18)19)11-8-10(9-17)5-6-12(11)21-16/h5-6,8,14-15,20H,3-4,7H2,1-2H3

Isómeros SMILES

CC1(C(C(C2=C(O1)C=CC(=C2)C#N)N3CCCC3=O)O)C

Peso molecular

286.33

Reaxy-Rn

8781733

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8781733&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Clase Benzopyrans
    - Subclass 1-benzopyrans

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Clase	Benzopyrans
Subclass	1-benzopyrans
Intermediate Tree Nodes	Not available
Direct Parent	2,2-dimethyl-1-benzopyrans
Alternative Parents	Alkyl aryl ethers Pyrrolidine-2-ones N-alkylpyrrolidines Benzenoids Tertiary carboxylic acid amides Secondary alcohols Lactams Oxacyclic compounds Nitriles Azacyclic compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	2,2-dimethyl-1-benzopyran - Alkyl aryl ether - Pyrrolidone - 2-pyrrolidone - N-alkylpyrrolidine - Benzenoid - Pyrrolidine - Tertiary carboxylic acid amide - Carboxamide group - Lactam - Secondary alcohol - Oxacycle - Azacycle - Carboxylic acid derivative - Ether - Carbonitrile - Nitrile - Hydrocarbon derivative - Organic oxide - Carbonyl group - Organopnictogen compound - Organonitrogen compound - Organooxygen compound - Organic oxygen compound - Alcohol - Organic nitrogen compound - Aromatic heteropolycyclic compound
Descripción	This compound belongs to the class of organic compounds known as 2,2-dimethyl-1-benzopyrans. These are organic compounds containing a 1-benzopyran moiety that carries two methyl groups at the 2-position.
External Descriptors	1-benzopyran
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Estructura 3D

Objetivos asociados (humanos)

KCNA7 Tclin Potassium voltage-gated channel subfamily A member 7 (1 Activities)

Discover Target: KCNA7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNC1 Tclin Potassium voltage-gated channel subfamily C member 1 (1 Activities)

Discover Target: KCNC1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNJ8 Tbio ATP-sensitive inward rectifier potassium channel 8 (0 Activities)

Discover Target: KCNJ8

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNJ11 Tclin ATP-sensitive inward rectifier potassium channel 11 (0 Activities)

Discover Target: KCNJ11

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ABCC9 Tclin Sulfonylurea receptor 2 (109 Activities)

Discover Target: ABCC9

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KCNJ11 Tclin Sulfonylurea receptors; K-ATP channels (596 Activities)

Discover Target: KCNJ11

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Objetivos asociados (no humanos)

Cavia porcellus (23802 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Canis familiaris (36305 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Sus scrofa (849 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Oryctolagus cuniculus (11301 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mus musculus (284745 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rattus norvegicus (775804 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A10 (235 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ATP5F1E Mitochondrial complex V; ATP synthase (114 Activities)

Discover Target: ATP5F1E

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Heart (171 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Aorta (2975 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Thoracic (21 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Certificados (CoA, COO, BSE/TSE y tabla de análisis)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Propiedades químicas y físicas

Solubilidad	Soluble in DMSO to 50 mM
Peso molecular	286.330 g/mol
XLogP3	0.800
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	1
Exact Mass	286.132 Da
Monoisotopic Mass	286.132 Da
Topological Polar Surface Area	73.600 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	481.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	2
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Calculadoras de soluciones

Molarity Calculator

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Dilution Calculator

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Reconstitution Calculator

Reseñas

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Bulk & Custom Packaging Need larger quantities or custom specifications? Contact our team for a tailored quote.

Cromakalim - Moligand™, ≥99% , Activator of K ir6.1;Activator of K ir6.2;Channel blocker of K v1.7;Channel blocker of K v3.1, CAS No.94470-67-4, Activator of K ir6.1;Activator of K ir6.2;Channel blocker of K v1.7;Channel blocker of K v3.1

Storage & shipping

Quality documents

Literature proof

Descripción general

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Reseñas de cliente

Need help choosing the grade?

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