Cycloheximide (NSC-185) - Moligand™, 10mM in DMSO , 80S Ribosome inhibitor, CAS No.66-81-9, 80S Ribosome inhibitor

CAS: 66-81-9 Cat. No.: C408230 Fórmula: C₁₅H₂₃NO₄ Peso molecular: 281.35 Número EC: 200-636-0

CALIDAD & PUREZA Moligand™, 10mM in DMSO

Synonyms

Actidione, Naramycin A, CHX, FT 3422-2, NM-MCD 80 | 4-[2-(3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs,FedEx DG Service

Descripción general

Information

Cycloheximide (NSC-185) Cycloheximide (NSC-185, Actidione, Naramycin A, CHX, FT 3422-2, NM-MCD 80), an antifungal antibiotic, is an eukaryote protein synthesis inhibitor with IC50 of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo,
In vitro

In vivo

Cell Data

cell lines：HT29, Colo205, PC-3, MDA-MB-231 and K562 cells

Concentrations：

Incubation Time：

Powder Purity:≥97%

Especificaciones

Sinónimos

Actidione, Naramycin A, CHX, FT 3422-2, NM-MCD 80 | 4-[2-(3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione

Especificaciones y pureza

Moligand™, 10mM in DMSO

Mecanismos bioquímicos y fisiológicos

Cycloheximide (NSC-185, Actidione, Naramycin A, CHX, FT 3422-2, NM-MCD 80), an antifungal antibiotic, is an eukaryote protein synthesis inhibitor with IC50 of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo, respectively. Cycloheximid

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs,FedEx DG Service

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

INHIBITOR

Mecanismo de acción

80S Ribosome inhibitor

Propiedades del producto

ALogP

0.5

Nombres e identificadores

Isómeros SMILES

C[C@H]1C[C@@H](C(=O)[C@@H](C1)[C@@H](CC2CC(=O)NC(=O)C2)O)C

Número ONU

2811

Grupo de embalaje

II

Peso molecular

281.35

Reaxy-Rn

9515475

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9515475&ln=

Objetivos asociados (humanos)

EIF4A1 Tchem Eukaryotic initiation factor 4A-I (0 Activities)

Discover Target: EIF4A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC2A1 Tchem Solute carrier family 2, facilitated glucose transporter member 1 (0 Activities)

Discover Target: SLC2A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Propiedades químicas y físicas

• Solubilidad: Solubility (25°C) In vitro DMSO: 53 mg/mL (79.62 mM); Water: Insoluble; Ethanol: Insoluble
• Punto de inflamación (°F): 230°F
• Punto de inflamación (°C): >110°C
• Punto de ebullición (°C): 492°C
• Punto de fusión (°C): 119.5-121°C

Preguntas frecuentes

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 66-81-9, the molecular formula is C15H23NO4, and the molecular weight is 281.35 g/mol.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.