Denatonium benzoate(THS 839) - Moligand™, 10 mM in DMSO , CAS No.3734-33-6

CAS: 3734-33-6 Cat. No.: D1499493 Molecular Weight: 446.58 Beilstein Registry Number: 8179408 EC Number: 223-095-2
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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Desiccated,Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Status
Price
Qty
1ml
D1499493-1ml
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$35.90
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Desiccated,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 4 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Denatonium benzoate (THS-839) is known as the most bitter compound and is commonly used as a deterrent (bittering agent) to activate different types of bitter taste receptors ( TAS2Rs ) with oral activity. Denatonium benzoate can enhance insulin secretion, has anti-inflammatory effects, and promotes allergy susceptibility .

Specifications

Specifications & Purity
Moligand™, 10 mM in DMSO
Storage
Desiccated, Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
ACTIVATOR
Names and Identifiers
Isomeric SMILES CC[N+](CC)(CC1=CC=CC=C1)CC(=O)NC2=C(C=CC=C2C)C.C1=CC=C(C=C1)C(=O)[O-]
WGK Germany 2
RTECS BO6650000
Molecular Weight 446.58
Beilstein 8179408
Reaxy-Rn 8179408
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8179408&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Flash Point(°F)212 °F
Flash Point(°C)100 °C
Melt Point(°C)160.0 to 164.0 °C
Documents & Articles
Citations of This Product
References
1. Liwei Zhang, Huiwen Sun, Ewald Grosse-Wilde, Long Zhang, Bill S. Hansson, Hany K.M. Dweck.  (2023)  Cross-generation pheromonal communication drives Drosophila oviposition site choice.  CURRENT BIOLOGY,      [PMID:37098339] [10.1016/j.cub.2023.03.090]
2. Guocai Liu, Wei Wen, Zhiyuan Zhao, Xin Huang, Yifan Li, Mingcong Qin, Zhichao Pan, Yunlong Guo, Yunqi Liu.  (2023)  Bionic Tactile-Gustatory Receptor for Object Identification Based on All-Polymer Electrochemical Transistor.  ADVANCED MATERIALS,  35  (24): (2300242).  [PMID:37025036] [10.1002/adma.202300242]
3. Jun Yang, Hao Guo, Nan-Ji Jiang, Rui Tang, Guo-Cheng Li, Ling-Qiao Huang, Joop J. A. van Loon, Chen-Zhu Wang.  (2021)  Identification of a gustatory receptor tuned to sinigrin in the cabbage butterfly Pieris rapae.  PLoS Genetics,  17  (7): (e1009527).  [PMID:34264948] [10.1371/journal.pgen.1009527]
4. Kai Ni, Bo Che, Rong Gu, Chunhong Wang, Hongyang Xu, Huiduo Li, Shiyan Cen, Mingzhi Luo, Linhong Deng.  (2024)  BitterDB database analysis plus cell stiffness screening identify flufenamic acid as the most potent TAS2R14-based relaxant of airway smooth muscle cells for therapeutic bronchodilation.  Theranostics,      [PMID:38389834] [10.7150/thno.92492]
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