Denatonium benzoate(THS 839) - Moligand™, 10 mM in DMSO , CAS No.3734-33-6

CAS: 3734-33-6 Cat. No.: D1499493 Fórmula: C₂₁H₂₉N₂O·C₇H₅O₂ Peso molecular: 446.58 Beilstein Registry Number: 8179408 Número EC: 223-095-2

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Denatonium benzoate (THS-839) is known as the most bitter compound and is commonly used as a deterrent (bittering agent) to activate different types of bitter taste receptors ( TAS2Rs ) with oral activity. Denatonium benzoate can enhance insulin secretion, has anti-inflammatory effects, and promotes allergy susceptibility .

Specifications

Especificaciones y pureza

Moligand™, 10 mM in DMSO

Condiciones de almacenamiento de almacenamiento

Desiccated,Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

ACTIVATOR

Nombres e identificadores

• Isómeros SMILES: CC[N+](CC)(CC1=CC=CC=C1)CC(=O)NC2=C(C=CC=C2C)C.C1=CC=C(C=C1)C(=O)[O-]
• WGK Alemania: 2
• RTECS: BO6650000
• Peso molecular: 446.58
• Beilstein: 8179408
• Reaxy-Rn: 8179408
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8179408&ln=

Propiedades químicas y físicas

• Punto de inflamación (°F): 212 °F
• Punto de inflamación (°C): 100 °C
• Punto de fusión (°C): 160.0 to 164.0 °C

Referencias

1. Liwei Zhang, Huiwen Sun, Ewald Grosse-Wilde, Long Zhang, Bill S. Hansson, Hany K.M. Dweck.  (2023)  Cross-generation pheromonal communication drives Drosophila oviposition site choice.  CURRENT BIOLOGY,      [PMID:37098339] [10.1016/j.cub.2023.03.090]

2. Guocai Liu, Wei Wen, Zhiyuan Zhao, Xin Huang, Yifan Li, Mingcong Qin, Zhichao Pan, Yunlong Guo, Yunqi Liu.  (2023)  Bionic Tactile-Gustatory Receptor for Object Identification Based on All-Polymer Electrochemical Transistor.  ADVANCED MATERIALS,  35  (24): (2300242).  [PMID:37025036] [10.1002/adma.202300242]

3. Jun Yang, Hao Guo, Nan-Ji Jiang, Rui Tang, Guo-Cheng Li, Ling-Qiao Huang, Joop J. A. van Loon, Chen-Zhu Wang.  (2021)  Identification of a gustatory receptor tuned to sinigrin in the cabbage butterfly Pieris rapae.  PLoS Genetics,  17  (7): (e1009527).  [PMID:34264948] [10.1371/journal.pgen.1009527]

4. Kai Ni, Bo Che, Rong Gu, Chunhong Wang, Hongyang Xu, Huiduo Li, Shiyan Cen, Mingzhi Luo, Linhong Deng.  (2024)  BitterDB database analysis plus cell stiffness screening identify flufenamic acid as the most potent TAS2R14-based relaxant of airway smooth muscle cells for therapeutic bronchodilation.  Theranostics,      [PMID:38389834] [10.7150/thno.92492]

Preguntas frecuentes

How should this product be stored?

Store at ?80 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 3734-33-6, the molecular formula is C28H34N2O3, and the molecular weight is 446.58 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.