DMNPE-caged Luciferin - BioReagent, Suitable for molecular biology, ≥98%(TLC) , CAS No.223920-67-0

CAS: 223920-67-0 Cat. No.: D1375504 Fórmula: C₂₁H₁₉N₃O₇S₂ Peso molecular: 489.52

GRADE & PURITY BioReagent, Suitable for molecular biology, ≥98%(TLC)

Synonyms

D-Luciferin 1- (4 | 5-dimethoxy-2- nitrophenyl) ethyl ester | DMNPE-caged D-luciferin | D-Luciferin 1-(4,5-dimethoxy-2-nitrophenyl)ethyl ester | DMNPE

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Application

Bioluminescence, Cell Viability Assay, In Vivo Imaging, Reporter Gene Assay

Descripción general

DMNPE-caged Luciferin is a photoactivatable probe that can easily penetrate the cell membrane, and by exposure to UV light it undergoes a photochemical decomposition liberating a Luciferin molecule. Once exposed to Luciferase enzyme expressed by the cells, Luciferin emits visible (and measurable) light. Using_x000D_this technique, imaging of luciferase activity was performed both in living cells and in mouse tumor xenograft, by intraperitoneal injection of the caged DMNPE luciferin.

Specifications

Sinónimos

D-Luciferin 1- (4 | 5-dimethoxy-2- nitrophenyl) ethyl ester | DMNPE-caged D-luciferin | D-Luciferin 1-(4,5-dimethoxy-2-nitrophenyl)ethyl ester | DMNPE

Especificaciones y pureza

BioReagent, Suitable for molecular biology, ≥98%(TLC)

Estabilidad y almacenamiento

Store at -20℃ long term (1800 days). Store in the dark.

Condiciones de almacenamiento de almacenamiento

Protected from light,Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

BioReagent, Suitable for molecular biology

Pureza

≥98%(TLC)

Product Line

Productos biológicos

Nombres e identificadores

Sonrisas canónicas

CC(C1=CC(=C(C=C1[N+](=O)[O-])OC)OC)OC(=O)C2CSC(=N2)C3=NC4=C(S3)C=C(C=C4)O

IUPAC Name

1-(4,5-dimethoxy-2-nitrophenyl)ethyl (4S)-2-(6-hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylate

InChIKey

VGEMOUFKGRGCNZ-LNUXAPHWSA-N

INCHI

1S/C21H19N3O7S2/c1-10(12-7-16(29-2)17(30-3)8-15(12)24(27)28)31-21(26)14-9-32-19(23-14)20-22-13-5-4-11(25)6-18(13)33-20/h4-8,10,14,25H,9H2,1-3H3/t10?,14-/m1/s1

Isómeros SMILES

CC(C1=CC(=C(C=C1[N+](=O)[O-])OC)OC)OC(=O)[C@H]2CSC(=N2)C3=NC4=C(S3)C=C(C=C4)O

Peso molecular

489.52

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Alpha amino acid esters

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: Alpha amino acid esters
• Alternative Parents: Cysteine and derivatives Nitrophenyl ethers Benzyloxycarbonyls Benzothiazoles Phenoxy compounds Nitroaromatic compounds Methoxybenzenes Anisoles Alkyl aryl ethers 1-hydroxy-2-unsubstituted benzenoids Imidothiolactones Thiazolines Thiazoles Heteroaromatic compounds Carboxylic acid esters Sulfenyl compounds Propargyl-type 1,3-dipolar organic compounds Organic oxoazanium compounds Monocarboxylic acids and derivatives Imidothioic acids and derivatives Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic zwitterions Organic oxoanionic compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Alpha-amino acid ester - Cysteine or derivatives - Nitrophenyl ether - Benzyloxycarbonyl - Nitrobenzene - 1,3-benzothiazole - Phenoxy compound - Nitroaromatic compound - Methoxybenzene - Phenol ether - Anisole - 1-hydroxy-2-unsubstituted benzenoid - Alkyl aryl ether - Imidothiolactone - Benzenoid - Monocyclic benzene moiety - Heteroaromatic compound - Meta-thiazoline - Thiazole - Azole - Organic nitro compound - C-nitro compound - Imidothioester - Carboxylic acid ester - Azacycle - Organoheterocyclic compound - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Allyl-type 1,3-dipolar organic compound - Sulfenyl compound - Organic oxoazanium - Monocarboxylic acid or derivatives - Imidothioic acid or derivatives - Ether - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organic zwitterion - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organic hyponitrite - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as alpha amino acid esters. These are ester derivatives of alpha amino acids.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Soluble in DMSO or DMF.
• Peso molecular: 489.500 g/mol
• XLogP3: 4.200
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 7
• Exact Mass: 489.066 Da
• Monoisotopic Mass: 489.066 Da
• Topological Polar Surface Area: 190.000 Ų
• Heavy Atom Count: 33
• Formal Charge: 0
• Complexity: 767.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1