DVD-445 - ≥98% , CAS No.2375846-41-4

CAS: 2375846-41-4 Cat. No.: D646599 Fórmula: C₂₅H₂₈F₂N₂O₄ Peso molecular: 458.50

CALIDAD & PUREZA ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

DVD-445 (Compound 7) is a potent peptidomimetic covalent thioredoxin reductase 1 (TrxR1) inhibitor with an IC 50 of 0.60 μM for rat TrxR1. DVD-445 has good anticancer application

In Vitro

DVD-445 (Compound 7) shows a cytotoxic effect in SH-SY5Y, U87, HaCaT cell lines and PBMCs with IC 50 s of 10.99 μM, 9.70 μM, 8.30 μM, 55.71 μM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:IC50: 0.60 μM (rat TrxR1)

Especificaciones

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

DVD-445 (Compound 7) is a potent peptidomimetic covalent thioredoxin reductase 1 (TrxR1) inhibitor with an IC 50 of 0.60 μM for rat TrxR1. DVD-445 has good anticancer application.

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥98%

Nombres e identificadores

Sonrisas canónicas

O=C(OCCN(C(C1=CC=C(F)C=C1)C(NC(C)(C)C)=O)C)/C=C/C(C2=CC=C(F)C=C2)=O

Peso molecular

458.50

Propiedades químicas y físicas

• Solubilidad: DMSO : 100 mg/mL (218.10 mM; ultrasonic and warming and heat to 60°C)