Dxd-d5 - 10mM in DMSO , CAS No.D661678(DMSO)
Disponible
SKU
D661678
Dxd-d 5 is a deuterium labeled Dxd. Dxd is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a) .
IC50& Target:Topoisomerase I 0.31 μM (IC 50 )
In Vitro:Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the phar
Biological Activity:Dxd-d 5 is a deuterium labeled Dxd. Dxd is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a) .
Más Información
| CAS | D661678(DMSO) |
|---|---|
| Concentración | 10mM in DMSO |
| Especificaciones y pureza | 10mM in DMSO |
| Condiciones de almacenamiento de almacenamiento | Protected from light,Desiccated,Store at -80°C |
| Enviado en | Dry ice packs + Cold packs |
| Product Description | Dxd-d 5 is a deuterium labeled Dxd. Dxd is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a) . IC50& Target:Topoisomerase I 0.31 μM (IC 50 ) In Vitro:Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the phar Biological Activity:Dxd-d 5 is a deuterium labeled Dxd. Dxd is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a) . |
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