Epiandrosterone - ≥99% , CAS No.481-29-8

CAS: 481-29-8 Cat. No.: E129418 Fórmula: C₁₉H₃₀O₂ Peso molecular: 290.4 Número EC: 207-563-3

CALIDAD & PUREZA ≥99%

Synonyms

EpiA | 3.beta.-Hydroxy-5.alpha.-androstan-17-one | SR-01000837513 | UNII-8TR252Z538 | A-androsterone;EpiA | AM20061868 | BDBM50236240 | 3-(tert-butyldimethylsilanyloxy)propionaldehyde | BSPBio_000460 | HY-I0352 | 3beta-Hydroxyetioallocholan-17-one | AC-16

Storage

Store at 2-8°C

Shipped In

Wet ice

Especificaciones

Sinónimos

EpiA | 3.beta.-Hydroxy-5.alpha.-androstan-17-one | SR-01000837513 | UNII-8TR252Z538 | A-androsterone;EpiA | AM20061868 | BDBM50236240 | 3-(tert-butyldimethylsilanyloxy)propionaldehyde | BSPBio_000460 | HY-I0352 | 3beta-Hydroxyetioallocholan-17-one | AC-16

Especificaciones y pureza

≥99%

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

AGONIST

Pureza

≥99%

Nombres e identificadores

Pubchem Sid

504758752

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504758752

Sonrisas canónicas

CC12CCC(CC1CCC3C2CCC4(C3CCC4=O)C)O

IUPAC Name

(3S,5S,8R,9S,10S,13S,14S)-3-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one

InChIKey

QGXBDMJGAMFCBF-LUJOEAJASA-N

INCHI

1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12-16,20H,3-11H2,1-2H3/t12-,13-,14-,15-,16-,18-,19-/m0/s1

Isómeros SMILES

C[C@]12CC[C@@H](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C)O

Peso molecular

290.4

Reaxy-Rn

2055720

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2055720&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Clase Steroids and steroid derivatives
      • Subclass Androstane steroids

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Clase: Steroids and steroid derivatives
• Subclass: Androstane steroids
• Intermediate Tree Nodes: Not available
• Direct Parent: Androgens and derivatives
• Alternative Parents: 3-beta-hydroxysteroids 17-oxosteroids Secondary alcohols Ketones Cyclic alcohols and derivatives Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic homopolycyclic compounds
• Substituents: Androgen-skeleton - 3-hydroxysteroid - 3-beta-hydroxysteroid - Oxosteroid - 17-oxosteroid - Hydroxysteroid - Cyclic alcohol - Secondary alcohol - Ketone - Organic oxygen compound - Organooxygen compound - Hydrocarbon derivative - Carbonyl group - Organic oxide - Alcohol - Aliphatic homopolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans.
• External Descriptors: C19 steroids (androgens) and derivatives

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)

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UGT1A4 Tbio UDP-glucuronosyltransferase 1A4 (288 Activities)

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CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

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HT-29 (80576 Activities)

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MCF7 (126967 Activities)

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T47D (39041 Activities)

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Jurkat (10389 Activities)

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LNCaP (8286 Activities)

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MDA-MB-231 (73002 Activities)

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UGT2B17 Tbio UDP-glucuronosyltransferase 2B17 (197 Activities)

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GPBAR1 Tchem G-protein coupled bile acid receptor 1 (1723 Activities)

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G6PD Tchem Glucose-6-phosphate 1-dehydrogenase (778 Activities)

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HSD17B7 Tchem 3-keto-steroid reductase (330 Activities)

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SNCA Tchem Alpha-synuclein (10960 Activities)

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UGT2B15 Tbio UDP-glucuronosyltransferase 2B15 (172 Activities)

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

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UGT1A1 Tchem UDP-glucuronosyltransferase 1-1 (448 Activities)

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GMNN Tbio Geminin (128009 Activities)

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SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

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CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)

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SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)

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UGT1A8 Tbio UDP-glucuronosyltransferase 1-8 (233 Activities)

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IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (40980 Activities)

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MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 Activities)

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TARDBP Tchem TAR DNA-binding protein 43 (40113 Activities)

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Objetivos asociados (no humanos)

Hdac6 Histone deacetylase 6 (222 Activities)

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Trypanosoma brucei (78846 Activities)

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Plasmodium falciparum (966862 Activities)

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Leishmania mexicana (936 Activities)

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Trypanosoma cruzi (99888 Activities)

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H9c2 (3506 Activities)

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Serine/threonine-protein phosphatase (23 Activities)

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GCN5 Histone acetyltransferase GCN5 (89 Activities)

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ATP-dependent molecular chaperone HSP82 (2186 Activities)

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NS1 Nonstructural protein 1 (33327 Activities)

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Mecanismos de acción

Propiedades químicas y físicas

• Peso molecular: 290.400 g/mol
• XLogP3: 3.700
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 290.225 Da
• Monoisotopic Mass: 290.225 Da
• Topological Polar Surface Area: 37.300 Ų
• Heavy Atom Count: 21
• Formal Charge: 0
• Complexity: 458.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 7
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1