≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
ERK Inhibitor is a cell-permeable thiazolidinedione compound that shows anti-proliferative properties. Binds preferentially to ERK2 with a KD of ~5 μM and prevents its interaction with protein substrates. The compound has been shown to block ERK-mediated phosphorylation of ribosomal S6 kinase-1 (RSK-1) and ternary complex factor Elk-1 in HeLa cells, while exhibiting minimal effect on ERK1/2 phosphorylation by MEK1/2.
| Pubchem Sid | 504768383 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504768383 |
| Canonical Smiles | CCOC1=CC=C(C=C1)C=C2C(=O)N(C(=O)S2)CCN.Cl |
| IUPAC Name | 3-(2-aminoethyl)-5-[(4-ethoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione;hydrochloride |
| InChIKey | PQVLWVGMXJPJLG-UHFFFAOYSA-N |
| INCHI | 1S/C14H16N2O3S.ClH/c1-2-19-11-5-3-10(4-6-11)9-12-13(17)16(8-7-15)14(18)20-12;/h3-6,9H,2,7-8,15H2,1H3;1H |
| Isomeric SMILES | CCOC1=CC=C(C=C1)C=C2C(=O)N(C(=O)S2)CCN.Cl |
| WGK Germany | 3 |
| Molecular Weight | 328.81 |
| Reaxy-Rn | 22507528 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=22507528&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
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| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 J22111043 | Certificate of Analysis | Jul 10, 2025 | E335372 |
| J22111044 | Certificate of Analysis | Jul 10, 2025 | E335372 |
| J22111061 | Certificate of Analysis | Jul 10, 2025 | E335372 |
| J22111062 | Certificate of Analysis | Jul 10, 2025 | E335372 |
| J22111063 | Certificate of Analysis | Jul 10, 2025 | E335372 |
| J22111064 | Certificate of Analysis | Jul 10, 2025 | E335372 |
| K2411101 | Certificate of Analysis | Sep 17, 2022 | E335372 |
| Solubility | Soluble in DMSO (≥4 mg/mL). |
|---|---|
| Refractive Index | n20D~1.65 (Predicted) |
