β-Estradiol 17-(β-D-glucuronide) sodium salt - ≥95% , CAS No.15087-02-2

CAS: 15087-02-2 Cat. No.: E337172 Fórmula: C₂₄H₃₁O₈·Na[XH₂O] Peso molecular: 470.5(anhydrous) Número EC: 633-986-1 PubChem CID: 86290017

GRADE & PURITY ≥95%

Synonyms

PD018024 | sodium 17beta-estradiol 17-glucosiduronate | Estradiol 17-(-D-Glucuronide) (sodium) | Q27156498 | CHEBI:82962 | HY-129987 | beta-D-Glucopyranosiduronic acid, (17beta)-3-hydroxyestra-1,3,5(10)-trien-17-yl, sodium salt (1:1) | sodium (17beta)-3-h

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

β-Estradiol 17-(β-D-glucuronide) sodium salt is a glucocorticosteroid estrogen metabolite formed in the liver, and excreted in bile. β-Estradiol 17-(β-D-glucuronide) sodium salt functions as a substrate of the multidrug resistance protein 2 (MRP2), and with its cholestatic agentry, β-Estradiol 17-(β-D-glucuronide) sodium salt can actually decrease bile flow. After binding to the MRP2 site, β-Estradiol 17-(β-D-glucuronide) sodium salt has been shown to bind to an allosteric site that activates its own transport via MRP2, and the transport of other MRP2 substrates including non-cholestatic estrogen metabolites. β-Estradiol 17-(β-D-glucuronide) sodium salt has also been observed being transported by MDR1, MRP1, MRP3, MRP4, MRP7, ABCG2, and rat organic anion-transporting polypeptides 1-4.

Specifications

Sinónimos

PD018024 | sodium 17beta-estradiol 17-glucosiduronate | Estradiol 17-(-D-Glucuronide) (sodium) | Q27156498 | CHEBI:82962 | HY-129987 | beta-D-Glucopyranosiduronic acid, (17beta)-3-hydroxyestra-1,3,5(10)-trien-17-yl, sodium salt (1:1) | sodium (17beta)-3-h

Especificaciones y pureza

≥95%

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥95%

Nombres e identificadores

Pubchem Sid

488202419

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488202419

Sonrisas canónicas

[H][C@@]12CCC3=CC(O)=CC=C3[C@@]1([H])CC[C@@]4(C) [C@@]2([H])CC[C@@H]4O[C@@]5([H])[C@H](O)[C@@H](O)[C@H](O)[C@@H](C([O-])=O)O5.[Na+].O

IUPAC Name

sodium;(2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[[(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]oxy]oxane-2-carboxylate

InChIKey

UQSHTUQZFYMYFO-VGYGJRAWSA-M

INCHI

1S/C24H32O8.Na/c1-24-9-8-14-13-5-3-12(25)10-11(13)2-4-15(14)16(24)6-7-17(24)31-23-20(28)18(26)19(27)21(32-23)22(29)30;/h3,5,10,14-21,23,25-28H,2,4,6-9H2,1H3,(H,29,30);/q;+1/p-1/t14-,15-,16+,17+,18+,19+,20-,21+,23-,24+;/m1./s1

Isómeros SMILES

C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)[O-])O)O)O)CCC5=C3C=CC(=C5)O.[Na+]

WGK Alemania

3

CAS alternativo

1806-98-0

PubChem CID

86290017

Peso molecular

470.5(anhydrous)

Propiedades químicas y físicas

• Solubilidad: DMSO (Slightly), Ethanol (Very Slightly), Methanol (Slightly)
• Sensibilidad: Moisture sensitive