Factor IXa Beta, CAS No.9001-28-9

CAS: 9001-28-9 Cat. No.: np330899

CALIDAD & PUREZA Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, from Human plasma; Pre-lyophilization Protein Concentration: See COA

Accession #

P00740

Bioactivity

See COA

Descripción general

Prepared from Human Factor IX by activation with Human Factor XIa. The XIa is removed after activation. Complete activation is observed by SDS-PAGE. The Factor XIa activates Factor IX in a two-step reaction. In the first step, an internal Arg-Ala bond is cleaved, and in the second step, an Arg-Val bond is cleaved. The second cleavage leads to the liberation of an activation peptide from the NH2-terminal portion of the heavy chain to produce Factor IXaβ.

Buffer composition = 50mM MES/0.6M NaCl/pH 6.0-NaOH

Extinction Coefficient (1%) = 14.3

Molecular Weight = 45,000 daltons

The above protein was purified from Human plasma that was tested and found negative by FDA accepted methods for Anti-HIV1/2, Anti-HTLV I & II, HBsAg, Anti-HCV, Syphilis, HBC Ab, HIV-1 p24 Ag or HIV-1 RNA, HCV RNA and HBV RNA.Donors are screened for CJD (Creutzfeldt-Jakob Disease).

Especificaciones

Product Name

Factor IXa Beta, CAS No.9001-28-9

Sinónimos

Human Factor IXa β | Human Factor IXa Beta | Human Factor IXa Beta Native Protein | Native Human Factor IXa Beta protein | Coagulation Factor IXa Beta Human | Factor IXab | Factor IXaβ | F9 | FIX | P19 | PTC | HEMB | THPH8 | F9 p22

Grado

ActiBioPure™, Bioactive, High Performance, Native, EnzymoPure™

Especificaciones y pureza

Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, from Human plasma; Pre-lyophilization Protein Concentration: See COA

Mecanismos bioquímicos y fisiológicos

Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ ions, phospholipids, and factor VIIIa. Post-translational: Activated by fac

Bioactividad

See COA

Número de adhesión

P00740

Peso molecular previsto

45 kDa

CAS

9001-28-9

Número de la Comisión de Enzimas

EC 3.4.21.22

Tipo de molécula

Enzima

Product Line

Productos biológicos

Almacenamiento y envío

Concentración

from Human plasma; Pre-lyophilization Protein Concentration: See COA

Reconstitución

We suggest hydrating the protein with a good quality water to the original volume (See COA). After hydration aliquot into a useful (one time use) size and freeze at -80℃.

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C

Enviado en

Wet ice

Estabilidad y almacenamiento

Store at 2-8℃ long term. Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle.