GRADE & PURITYBioactive?Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure.ActiBioPure™?ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required.Native?Native grade — protein/biomolecule in its natural (non-recombinant, non-denatured) form. Use when native structure and activity are required.High Performance?High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short.EnzymoPure™?EnzymoPure™ — Aladdin's line of high-quality enzymatic solutions. Use when enzyme purity and defined activity drive assay or process performance.from Human plasma; Protein concentration: See COA
Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, from Human plasma; Protein concentration: See COA ActiBioPure™,Bioactive,High Performance,Native,EnzymoPure™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Human factor XIII is cleaved with human alpha thrombin that is immobilized to a resin. The thrombin is subsequently removed via chromatography. One plasma equivalent unit (PEU) is equal to ~108 Loewy units.
Buffer composition = 0.05mM EDTA/ 50% glycerol
Extinction Coefficient (1%)=13.8
Molecular Weight = 312,000 daltons
The above protein was purified from Human plasma units that test negative for antibodies to HBc, HCV, HIV 1/2, HTLV-I/II, and non reactive for HBsAg, HIV-1 RNA, HCV RNA, HBV DNA and Syphilis by FDA approved tests. Donors are screened for CJD.
If diluting, use physiologic buffer such as TBS containing 0.5mM EDTA.
Specifications
Product Name
Factor XIII
Grade
ActiBioPure™, Bioactive, High Performance, Native, EnzymoPure™
Specifications & Purity
Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, from Human plasma; Protein concentration: See COA
Biochemical and Physiological Mechanisms
Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fib
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Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
