Recombinant Human GOLGA8M Protein: FAQs & Key Facts

Recombinant Human GOLGA8M Protein is a research-grade recombinant protein derived from the human GOLGA8M gene, offered by Aladdin Scientific (SKU: rp377483) to support studies related to Golgi apparatus structure and function.

Product Name

Recombinant Human GOLGA8M Protein

SKU

rp377483

Gene / Protein Family

GOLGA8M; Golgin A8 family member M; Golgi apparatus associated protein

Species Origin

Human (Homo sapiens)

Supplier

Aladdin Scientific

Content Type

FAQ – Technical & Ordering Guidance

What Is GOLGA8M and Why Is It Studied?

GOLGA8M (Golgin A8 Family Member M) is a member of the golgin protein family, a group of coiled-coil proteins localized to the Golgi apparatus. Golgins play essential roles in maintaining Golgi structure, mediating vesicle tethering, and regulating intracellular trafficking pathways. GOLGA8M is encoded by a gene on chromosome 15 within a region subject to copy-number variation, which has attracted interest in the context of neurodevelopmental research.

Recombinant versions of GOLGA8M are used in biochemical assays, protein interaction studies, and as antigens for antibody validation. Research scientists studying Golgi dynamics, membrane trafficking, or chromosomal copy-number variation biology may find this protein relevant to their work.

Product Specifications and Quality Information

Aladdin Scientific's Recombinant Human GOLGA8M Protein (SKU: rp377483) is produced as a recombinant protein intended for research use. For precise details regarding expression host (e.g., E. coli, baculovirus, or mammalian system), tag configuration, molecular weight, purity grade, formulation buffer, and endotoxin levels, please refer to the official product datasheet available on the Aladdin Scientific website or contact our technical support team directly.

All Aladdin Scientific recombinant proteins undergo quality control testing prior to release. Typical QC methods for recombinant proteins in this category include SDS-PAGE analysis for purity assessment and appropriate functional or binding assays where applicable.

Storage, Handling, and Stability

Recombinant proteins are sensitive biological reagents that require careful handling to maintain activity and integrity. As a general guideline for proteins of this class:

• Store at –20 °C or –80 °C upon receipt for long-term storage, as specified on the product datasheet.
• Avoid repeated freeze-thaw cycles; aliquot the protein into single-use volumes where possible.
• Keep on ice during working sessions and minimize exposure to elevated temperatures or denaturing conditions.
• Refer to the product-specific datasheet for recommended reconstitution conditions if the protein is supplied in lyophilized form.

Always consult the official Aladdin Scientific datasheet for product-specific storage instructions, as conditions may vary by formulation.

Recommended Applications

Recombinant Human GOLGA8M Protein is intended for research applications. Typical uses for recombinant golgin-family proteins include:

• In vitro binding assays: Investigating protein–protein interactions involving GOLGA8M.
• Antibody development and validation: Serving as a well-defined antigen for generating or validating GOLGA8M-specific antibodies.
• Structural and biochemical studies: Characterizing the biophysical properties of GOLGA8M coiled-coil domains.
• Cell-free functional assays: Supporting mechanistic studies of Golgi tethering or trafficking processes.

This product is for research use only (RUO) and is not approved for diagnostic, therapeutic, or clinical applications.

Ordering, Pricing, and Customer Support

Recombinant Human GOLGA8M Protein (SKU: rp377483) can be ordered directly through the Aladdin Scientific website or by contacting our sales team. For current pricing, available pack sizes, lead times, and bulk order inquiries, please visit the product page or reach out to Aladdin Scientific customer service.

For technical questions regarding experimental design, protein handling, or application-specific recommendations, our technical support team is available to assist. Returns and refunds are handled in accordance with Aladdin Scientific's standard returns policy; please refer to the relevant policy page on our website for details.

Frequently asked questions

What is Recombinant Human GOLGA8M Protein and what is its biological relevance?

Recombinant Human GOLGA8M Protein is a recombinant form of the human GOLGA8M gene product, a member of the golgin coiled-coil protein family associated with the Golgi apparatus. Golgins like GOLGA8M are implicated in Golgi structural integrity and vesicle tethering. The GOLGA8M gene resides in a chromosomal region prone to copy-number variation, making it of interest in neurodevelopmental and genomic stability research.

What expression system is used to produce Recombinant Human GOLGA8M Protein (rp377483)?

The specific expression host and production details for SKU rp377483 are provided in the official Aladdin Scientific product datasheet. Common expression systems for recombinant human proteins include E. coli, baculovirus-insect cell, and mammalian cell systems, each offering different glycosylation profiles and folding environments. Please consult the datasheet or contact our technical support for confirmed production details.

How should Recombinant Human GOLGA8M Protein be stored to maintain stability?

As a general best practice, recombinant proteins should be stored at –20 °C or –80 °C upon receipt and should not be subjected to repeated freeze-thaw cycles; single-use aliquots are recommended. The precise storage conditions, recommended buffer, and shelf-life information for rp377483 are specified on the Aladdin Scientific product datasheet and should always be followed.

What quality control testing does Aladdin Scientific perform on this recombinant protein?

Aladdin Scientific performs quality control testing on recombinant proteins prior to release. Standard QC procedures for recombinant proteins typically include SDS-PAGE analysis to confirm purity and apparent molecular weight, and may include functional or binding assays depending on the protein. Specific QC data for rp377483 are available on the product datasheet or upon request from our technical support team.

Can Recombinant Human GOLGA8M Protein be used in diagnostic or clinical applications?

No. Recombinant Human GOLGA8M Protein (rp377483) is designated for research use only (RUO) and has not been validated or approved for diagnostic, therapeutic, or any clinical application. Use of this product outside a research context is not supported by Aladdin Scientific.

References

1. Bekpen C, et al. Segmental duplications and complex genomic rearrangements involving the GOLGA8 gene family on chromosome 15q. (General reference on GOLGA8 gene family and copy-number variation biology — specific citation details require verification.)
2. Munro S. The golgin coiled-coil proteins of the Golgi apparatus. Cold Spring Harb Perspect Biol. (General reference on golgin biology — specific volume, page, and year require verification.)
3. Aladdin Scientific. Recombinant Human GOLGA8M Protein, SKU rp377483. Product Datasheet. Aladdin Scientific (www.aladdinscientific.com).

Products are supplied for research and development use only. Not for use in humans, animals, diagnosis, or therapy.