1,4-diazacyclohexane

Piperazine Selection Guide: Using a “Six-Membered Diaza Ring” to Make Salt Forms and Linking Strategies More Controllable (Appendix Tables 1–4 Product Navigator)

Piperazine is a saturated six-membered nitrogen heterocycle with two nitrogen atoms at the 1,4-positions (opposite each other on the ring). It can therefore also be called 1,4-diazacyclohexane. Unsubstituted piperazine is essentially a cyclic diamine (both nitrogens are secondary amines), which ...