GeA-69 - ≥99% , CAS No.2143475-98-1

CAS: 2143475-98-1 Cat. No.: G412515 Fórmula: C20H16N2O Peso molecular: 300.35
Disponible para pedir
GRADE & PURITY ≥99%
Synonyms
N-[2-(9H-Carbazol-1-yl)phenyl]-acetamide
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
Size
Alemania (EU)
USA*
Price
Qty
5mg
G412515-5mg
—
2 Disponible

25,08€

38,09€
Guardar 13,02 € (34.17%)
25mg
G412515-25mg
—
2 Disponible

91,89€

137,88€
Guardar 45,99 € (33.35%)
50mg
G412515-50mg
—
2 Disponible

155,24€

233,34€
Guardar 78,10 € (33.47%)
100mg
G412515-100mg
—
2 Disponible

280,19€

420,77€
Guardar 140,57 € (33.41%)
250mg
G412515-250mg
—
2 Disponible

611,67€

917,98€
Guardar 306,31 € (33.37%)
Enter a quantity for the sizes you want to add.
🧪
Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Information

GeA-69 GeA-69 is a cell-permeable, selective allosteric inhibitor targeting macrodomain 2 (MD2) of poly-adenosine-diphosphate-ribose polymerase 14 (PARP14) with Kd of 860 nM.


Targets

PARP14-MD2 (Cell-free assay) 860 nM(Kd)

Specifications

Sinónimos
N-[2-(9H-Carbazol-1-yl)phenyl]-acetamide
Especificaciones y pureza
≥99%
Mecanismos bioquímicos y fisiológicos
GeA-69 is a cell-permeable, selective allosteric inhibitor targeting macrodomain 2 (MD2) of poly-adenosine-diphosphate-ribose polymerase 14 (PARP14) with Kd of 860 nM.
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Pureza
≥99%
Propiedades del producto
ALogP
3.962
hba_count
1
Recuento HBD
2
Enlace rotable
2
Nombres e identificadores
Pubchem Sid
Pubchem Sid Url
https://pubchem.ncbi.nlm.nih.gov/substance/528764743
Sonrisas canónicas
CC(=O)NC1=CC=CC=C1C2=CC=CC3=C2NC4=CC=CC=C34
IUPAC Name
N-[2-(9H-carbazol-1-yl)phenyl]acetamide
InChIKey
LDPDVNYCIOHPGF-UHFFFAOYSA-N
INCHI
1S/C20H16N2O/c1-13(23)21-18-11-4-2-7-14(18)16-9-6-10-17-15-8-3-5-12-19(15)22-20(16)17/h2-12,22H,1H3,(H,21,23)
Isómeros SMILES
CC(=O)NC1=CC=CC=C1C2=CC=CC3=C2NC4=CC=CC=C34
Peso molecular
300.35
Reaxy-Rn
32144804
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=32144804&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClaseIndoles and derivatives
SubclassCarbazoles
Intermediate Tree Nodes Not available
Direct ParentCarbazoles
Alternative Parents Acetanilides  N-acetylarylamines  Indoles  Pyrroles  Heteroaromatic compounds  Acetamides  Secondary carboxylic acid amides  Azacyclic compounds  Organopnictogen compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Carbazole - Acetanilide - N-acetylarylamine - Anilide - Indole - N-arylamide - Benzenoid - Monocyclic benzene moiety - Heteroaromatic compound - Acetamide - Pyrrole - Secondary carboxylic acid amide - Carboxamide group - Azacycle - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Carbonyl group - Aromatic heteropolycyclic compound
DescripciónThis compound belongs to the class of organic compounds known as carbazoles. These are compounds containing a three ring system containing a pyrrole ring fused on either side to a benzene ring.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
PARP14 Tchem Poly [ADP-ribose] polymerase 14 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeFechaArticulo
I2216047Certificate of AnalysisJun 16, 2025 G412515
I2216046Certificate of AnalysisJun 16, 2025 G412515
I2216045Certificate of AnalysisJun 16, 2025 G412515
I2216043Certificate of AnalysisJun 10, 2025 G412515
I2216044Certificate of AnalysisJun 10, 2025 G412515
C2524069Certificate of AnalysisJul 07, 2022 G412515
Propiedades químicas y físicas
SolubilidadSolubility (25°C) In vitro DMSO: 60 mg/mL (199.76 mM); Ethanol: 10 mg/mL (33.29 mM); Water: Insoluble;
SensibilidadMoisture sensitive
DMSO (mg/ml) Solubilidad máxima60
DMSO (mM) Solubilidad máxima199.766938571666
Agua (mg/ml) Solubilidad máxima<1
Peso molecular300.400 g/mol
XLogP34.200
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count1
Rotatable Bond Count2
Exact Mass300.126 Da
Monoisotopic Mass300.126 Da
Topological Polar Surface Area44.900 Ų
Heavy Atom Count23
Formal Charge0
Complexity437.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculadoras de soluciones
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