Determine the necessary mass, volume, or concentration for preparing a solution.
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10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 20 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Tributyrin is a short-chain triacylglycerol that mainly occurs in butter. It shows potent anti-cancer property.
| Canonical Smiles | CCCC(=O)OCC(COC(=O)CCC)OC(=O)CCC |
|---|---|
| IUPAC Name | 2,3-di(butanoyloxy)propyl butanoate |
| InChIKey | UYXTWWCETRIEDR-UHFFFAOYSA-N |
| INCHI | 1S/C15H26O6/c1-4-7-13(16)19-10-12(21-15(18)9-6-3)11-20-14(17)8-5-2/h12H,4-11H2,1-3H3 |
| Isomeric SMILES | CCCC(=O)OCC(COC(=O)CCC)OC(=O)CCC |
| WGK Germany | 1 |
| RTECS | ET7350000 |
| Molecular Weight | 302.36 |
| Beilstein | 1714746 |
| Reaxy-Rn | 1714746 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1714746&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Lipids and lipid-like molecules |
| Class | Glycerolipids |
| Subclass | Triradylcglycerols |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Triacylglycerols |
| Alternative Parents | Tricarboxylic acids and derivatives Fatty acid esters Carboxylic acid esters Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Triacyl-sn-glycerol - Tricarboxylic acid or derivatives - Fatty acid ester - Fatty acyl - Carboxylic acid ester - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic acyclic compound |
| Description | This compound belongs to the class of organic compounds known as triacylglycerols. These are glycerides consisting of three fatty acid chains covalently bonded to a glycerol molecule through ester linkages. |
| External Descriptors | a triacylglycerol |
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| Refractive Index | 1.4350 to 1.4380 |
|---|---|
| Flash Point(°F) | 180°C |
| Flash Point(°C) | 180°C |
| Boil Point(°C) | 190°C/15mmHg |
| Melt Point(°C) | -75°C |
| Molecular Weight | 302.360 g/mol |
| XLogP3 | 2.400 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 14 |
| Exact Mass | 302.173 Da |
| Monoisotopic Mass | 302.173 Da |
| Topological Polar Surface Area | 78.900 Ų |
| Heavy Atom Count | 21 |
| Formal Charge | 0 |
| Complexity | 304.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Chunyun Qu, Liying Peng, Yongtao Fei, Jinglong Liang, Weidong Bai, Gongliang Liu. (2023) Screening ester-producing yeasts to fortify the brewing of rice-flavor Baijiu for enhanced aromas. Bioengineered, [PMID:37715575] [10.1080/21655979.2023.2255423] |
| 2. Kai Luo, Yuhui Shi, Kunlin Yang, Qiaoqing Xu, Jiang Zhou, Weihua Gao, Chenglong Wu, Zhuoduo Wang. (2023) Effects of dietary tributyrin supplementation in low fish meal diet containing high-Clostridium autoethanogenum protein on the growth performance, antioxidative capacity, lipid metabolism and intestinal microbiota of largemouth bass (Micropterus salmoides). Aquaculture Reports, [PMID:] [10.1016/j.aqrep.2023.101722] |
| 3. Qirui Tian, Weiqing Zhou, Qiong Cai, Xiaoyun Pan, Guanghui Ma, Guoping Lian. (2022) In situ complex coacervation supported by self-coated polydopamine interlayer on uniform-sized essential oils droplet. JOURNAL OF COLLOID AND INTERFACE SCIENCE, [PMID:] [10.1016/j.jcis.2022.05.072] |
| 4. Qian Wang, Meiling Ge, Xuan Guo, Zhijun Li, Agen Huang, Fu Yang, Rong Guo. (2021) Hydrophobic poly(ionic liquid)s as “two-handed weapons”: Maximizing lipase catalytic efficiency in transesterification of soybean oil toward biodiesel. APPLIED CATALYSIS A-GENERAL, [PMID:] [10.1016/j.apcata.2021.118350] |
| 5. Jianping Wang, Hongye Zhang, Shiping Bai, Qiufeng Zeng, Zhuowei Su, Yong Zhuo, Xiangbing Mao, Huadong Yin, Bin Feng, Jingbo Liu, Keying Zhang, Xuemei Ding. (2021) Dietary tributyrin improves reproductive performance, antioxidant capacity, and ovary function of broiler breeders. POULTRY SCIENCE, [PMID:34555757] [10.1016/j.psj.2021.101429] |
| 6. Yao Jian, Gui Lun, Yin Shaocheng. (2021) A novel esterase from a soil metagenomic library displaying a broad substrate range. AMB Express, 11 (1): (1-10). [PMID:33666762] [10.1186/s13568-021-01198-5] |
| 7. Zeng Liya, Liu Yongchang, Pan Jun, Liu Xiaowen. (2019) Formulation and evaluation of norcanthridin nanoemulsions against the Plutella xylostella (Lepidotera: Plutellidae). BMC BIOTECHNOLOGY, 19 (1): (1-11). [PMID:30871528] [10.1186/s12896-019-0508-8] |
| 8. Tao Meng, Ruixue Bai, Weihao Wang, Xin Yang, Ting Guo, Yaolei Wang. (2019) Enzyme-Loaded Mesoporous Silica Particles with Tuning Wettability as a Pickering Catalyst for Enhancing Biocatalysis. Catalysts, 9 (1): (78). [PMID:] [10.3390/catal9010078] |
| 9. Ling-Zhi Cheong, Chenyu Jiang, Xiaoqian He, Shuang Song, Oi-Ming Lai. (2018) Lipid Profiling, Particle Size Determination, and in Vitro Simulated Gastrointestinal Lipolysis of Mature Human Milk and Infant Formula. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:30362342] [10.1021/acs.jafc.8b03998] |
| 10. Liya Zeng, Yalin Zhang. (2017) Development, optimization and in vitro evaluation of norcantharidin loadedself-nanoemulsifying drug delivery systems (NCTD-SNEDDS). PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, [PMID:27487261] [10.1080/10837450.2016.1219915] |
| 11. Jie Sun, Liang Chen, Bo Lou, Yanbing Bai, Xinjun Yu, Man Zhao, Zhao Wang. (2017) Acetylation and deacetylation for sucralose preparation by a newly isolated Bacillus amyloliquefaciens WZS01. JOURNAL OF BIOSCIENCE AND BIOENGINEERING, [PMID:28131539] [10.1016/j.jbiosc.2016.12.013] |
| 12. Qinzhou Cai, Huifang Zhang, Bingshan Zhao, Lei Ren, Yonghua Wang, Fanghua Wang. (2024) A cold-adapted and robust alkaline lipase from Marinobacter nanhaiticus boosts laundry detergent performance. JOURNAL OF SURFACTANTS AND DETERGENTS, [PMID:] [10.1002/jsde.12793] |
| 13. Qirui Tian, Weiqing Zhou, Qiong Cai, Xiaoyun Pan, Guanghui Ma, Guoping Lian. (2024) Bi-layered oil encapsulates formed by polydopamine-supported in situ complex coacervation: Investigation of structure formation and sustained release performance. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, [PMID:] [10.1016/j.colsurfa.2024.133976] |
| 14. Cui Kun, Zhang Hanle, Yun Biao, Wang Jianxue, Qian Xueqiao, Xue Min. (2024) Dietary supplementation with sodium propionate and tributyrin alleviated hepatic lipid deposition and improved the antioxidant capacity and hypoxic stress resistance of spotted seabass (Lateolabrax maculatus). Frontiers in Marine Science, [PMID:] [10.3389/fmars.2024.1481672] |
| 15. Bowen Yang, Cheng Chen, Weisu Huang, Tian Zhao, Shengyang Ji, Yan Liu, Baiyi Lu. (2024) Encapsulation of antioxidants with colloidal lipid particles for enhancing the photooxidation stability of phytosterol in Pickering emulsions. FOOD CHEMISTRY, [PMID:38744126] [10.1016/j.foodchem.2024.139474] |
| 16. Bowen Yang, Tian Zhao, Shengyang Ji, Yan Liu, Minghao Xu, Baiyi Lu. (2024) Molecular dynamics simulations of the interfacial behaviors and photo-oxidation of phytosterol under different emulsion oil content. FOOD CHEMISTRY, [PMID:38663239] [10.1016/j.foodchem.2024.139292] |
| 17. Mingjie Xia, Yangyang Zhang, Lina Yang, Hong Song, Jun Li, Guangchen Zhang, He Liu. (2025) Soy hull polysaccharide encapsulated tributyrin delivery system exhibits gut microbiota responsive release and improved high butyric acid state in vitro. Food Bioscience, [PMID:] [10.1016/j.fbio.2025.106051] |
| 18. Wenjing Chen, Sha Li, Amgad Albahi, Shuxin Ye, Jing Li, Bin Li. (2024) The effect of konjac glucomannan on enzyme kinetics and fluorescence spectrometry of digestive enzymes: An in vitro research from the perspective of macromolecule crowding. FOOD RESEARCH INTERNATIONAL, [PMID:38609226] [10.1016/j.foodres.2024.114247] |
| 19. Gege Sun, Wenbo Li, Donghui Li, Xianwen Hu, Bin Li, David Julian McClements, Shilin Liu, Kaikai Li, Yan Li. (2025) Amelioration of Colitis Using Colonic Microbiota-Stimulated Release of Tributyrin from Pickering Emulsion-Filled Alginate Beads. LANGMUIR, [PMID:40695562] [10.1021/acs.langmuir.5c02248] |
| 20. Zixian Liang, Jiahao Zhang, Qinyi Cao, Wanyuan Li, Yuting Dai, Yining Zhao, Leyan Ou, Dapeng Lei, Kunfeng Liu, Zonghua Luo, Ze Xiong, Guihua Jiang, Yin Ning, Jizhuang Wang, Jinyao Tang, Dan Li. (2025) MOF-based magnetically manipulated microwheel-robots for triglyceride degradation. Matter, [PMID:] [10.1016/j.matt.2025.102198] |