10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
GPR40 agonist 6 (Compound 7a) is a potent and selective free fatty acid receptor 1 ( FFAR1 or GPR40 ) agonist with an EC 50 of 0.058 μM
In Vitro
GPR40 agonist 6 (Compound 7a) shows a very favorable ADME profile, and shows no significant inhibition of the principal cytochrome P450 isoforms (1A2, 2C9, 2C19, 2D6 and 3A4) at 5 µM. ADME profile for GPR40 agonist 6 (Compound 7a)GPR40 agonist 6 (Compound 7a) Plasma protein binding (human) a 98.6% Aqueous solubility (PBS, pH 7.4) b 404 µM Microsomal stability (mouse, t1/2) c 434 min A-B permeability (Caco-2, cm•s -1 ) d 15.2 • 10 -6 a Each value is an average of n = 4, measured at c = 1 µM. b Each value is an average of n = 2. c Each value is an average of n = 5, measured at c = 2 µM. d Each value is an average of n = 2, measured at c = 10 µM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
IC50& Target:EC 50 : 0.058 μM (GPR40)
Specifications
Especificaciones y pureza
10mM in DMSO
Mecanismos bioquímicos y fisiológicos
GPR40 agonist 6 (Compound 7a) is a potent and selective free fatty acid receptor 1 ( FFAR1 or GPR40 ) agonist with an EC 50 of 0.058 μM.
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Tipo de acción
AGONIST
Nombres e identificadores
Peso molecular
337.37
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Calculadoras de soluciones
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Reseñas
Reseñas de cliente
Preguntas frecuentes
How should this product be stored?
Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 1798751-25-3, the molecular formula is C20H19NO4, and the molecular weight is 337.37 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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