Guanethidine Monosulfate - 10mM in Water , Norepinephrine transporter substrate, CAS No.645-43-2, Norepinephrine transporter substrate

CAS: 645-43-2 Cat. No.: G425271 Fórmula: C₁₀H₂₄N₄O₄S Peso molecular: 296.39 Número EC: 211-442-0

CALIDAD & PUREZA 10mM in Water

Synonyms

guanethidine sulfate|Guanethidine monosulfate|645-43-2|Ismelin|Ismelin sulfate|Guanethidine (sulfate)|Guanethidine Sulphae|guanethidine monosulphate|EINECS 211-442-0|UNII-5UBY8Y002G|Iporal|5UBY8Y002G|1-(2-(azocan-1-yl)ethyl)guanidine sulfate|N-(2-Guanidin

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Guanethidine monosulfate is an antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves.

Especificaciones

Sinónimos

guanethidine sulfate | Guanethidine monosulfate | 645-43-2 | Ismelin | Ismelin sulfate | Guanethidine (sulfate) | Guanethidine Sulphae | guanethidine monosulphate | EINECS 211-442-0 | UNII-5UBY8Y002G | Iporal | 5UBY8Y002G | 1-(2-(azocan-1-yl)ethyl)guanidine sulfate | N-(2-Guanidin

Especificaciones y pureza

10mM in Water

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

SUBSTRATE

Mecanismo de acción

Norepinephrine transporter substrate

Nombres e identificadores

Pubchem Sid

528774974

Sonrisas canónicas

C1CCCN(CCC1)CCN=C(N)N.OS(=O)(=O)O

IUPAC Name

2-[2-(azocan-1-yl)ethyl]guanidine;sulfuric acid

InChIKey

YUFWAVFNITUSHI-UHFFFAOYSA-N

INCHI

1S/C10H22N4.H2O4S/c11-10(12)13-6-9-14-7-4-2-1-3-5-8-14;1-5(2,3)4/h1-9H2,(H4,11,12,13);(H2,1,2,3,4)

Isómeros SMILES

C1CCCN(CCC1)CCN=C(N)N.OS(=O)(=O)O

Peso molecular

296.39

Reaxy-Rn

18292174

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=18292174&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Organic sulfuric acids and derivatives
      • Subclass Organic sulfuric acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Organic sulfuric acids and derivatives
• Subclass: Organic sulfuric acids
• Intermediate Tree Nodes: Not available
• Direct Parent: Organic sulfuric acids
• Alternative Parents: Trialkylamines Guanidines Propargyl-type 1,3-dipolar organic compounds Carboximidamides Azacyclic compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Sulfuric acid - Guanidine - Tertiary amine - Tertiary aliphatic amine - Carboximidamide - Azacycle - Organoheterocyclic compound - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Amine - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Aliphatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as organic sulfuric acids. These are organic compounds containing the sulfuric acid functional group, with the generic structure HOS(=O)(=O)OH.
• External Descriptors: organic sulfate salt

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Objetivos asociados (no humanos)

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Sensibilidad: Hygroscopic
• Punto de fusión (°C): 227℃
• Peso molecular: 296.390 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 296.152 Da
• Monoisotopic Mass: 296.152 Da
• Topological Polar Surface Area: 151.000 Ų
• Heavy Atom Count: 19
• Formal Charge: 0
• Complexity: 248.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3