Ilaprazole sodium - ≥98% , CAS No.172152-50-0

CAS: 172152-50-0 Cat. No.: I413292 Molecular Weight: 388.42

GRADE & PURITY ≥98%

Synonyms

AKOS037515492 | HY-B2145 | 1H-Benzimidazole, 2-(((4-methoxy-3-methyl-2-pyridinyl)methyl)sulfinyl)-6-(1H-pyrrol-1-yl)-, sodium salt (1:1) | Ilaprazole sodium | sodium;2-[(4-methoxy-3-methylpyridin-2-yl)methylsulfinyl]-5-pyrrol-1-ylbenzimidazol-3-ide | IY-8

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Information

Ilaprazole sodium Ilaprazole (IY-81149) sodium is the sodium salt form of ilaprazole, which is a proton pump inhibitor. Ilaprazole sodium irreversibly inhibits H(+)/K(+)-ATPase in a dose-dependent manner with IC50 of 6 μM in rabbit parietal cell preparation.

Targets

Proton pump ; H(+)/K(+)-ATPase (in rabbit parietal cell preparation) ; 6 μM

Specifications

Synonyms

AKOS037515492 | HY-B2145 | 1H-Benzimidazole, 2-(((4-methoxy-3-methyl-2-pyridinyl)methyl)sulfinyl)-6-(1H-pyrrol-1-yl)-, sodium salt (1:1) | Ilaprazole sodium | sodium;2-[(4-methoxy-3-methylpyridin-2-yl)methylsulfinyl]-5-pyrrol-1-ylbenzimidazol-3-ide | IY-8

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

Ilaprazole (IY-81149) sodium is the sodium salt form of ilaprazole, which is a proton pump inhibitor. Ilaprazole sodium irreversibly inhibits H(+)/K(+)-ATPase in a dose-dependent manner with IC50 of 6 μM in rabbit parietal cell preparation.

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Product Properties

• ALogP: 3.414
• hba_count: 4
• Rotatable Bond: 5

Names and Identifiers

• Pubchem Sid: 488202692
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488202692
• Canonical Smiles: CC1=C(C=CN=C1CS(=O)C2=NC3=C([N-]2)C=C(C=C3)N4C=CC=C4)OC.[Na+]
• IUPAC Name: sodium;2-[(4-methoxy-3-methylpyridin-2-yl)methylsulfinyl]-5-pyrrol-1-ylbenzimidazol-3-ide
• InChIKey: ZQGDDMFDBZPGCD-UHFFFAOYSA-N
• INCHI: 1S/C19H17N4O2S.Na/c1-13-17(20-8-7-18(13)25-2)12-26(24)19-21-15-6-5-14(11-16(15)22-19)23-9-3-4-10-23;/h3-11H,12H2,1-2H3;/q-1;+1
• Isomeric SMILES: CC1=C(C=CN=C1CS(=O)C2=NC3=C([N-]2)C=C(C=C3)N4C=CC=C4)OC.[Na+]
• Molecular Weight: 388.42
• Reaxy-Rn: 21526395
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=21526395&ln=

Chemical and Physical Properties

• Solubility: Solubility (25°C) In vitro DMSO: 78 mg/mL (200.81 mM)
• DMSO(mg / mL) Max Solubility: 78
• DMSO(mM) Max Solubility: 200.81355234025
• Water(mg / mL) Max Solubility: -1