IMR-1A - ≥97% , CAS No.331862-41-0

CAS: 331862-41-0 Cat. No.: I412257 Fórmula: C₁₃H₁₁NO₅S₂ Peso molecular: 325.36

GRADE & PURITY ≥97%

Synonyms

Acetic acid,2-​[2-​methoxy-​4-​[(4-​oxo-​2-​thioxo-​5-​thiazolidinylidene)​methyl]​phenoxy]​-

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

Information

IMR-1A IMR-1A, an acid metabolite of IMR-1, is a potent inhibitor of Notch with IC50 of 0.5 μM and Kd of 2.9 μM. IMR-1A exhibits anti-tumor activity.

Targets

Notch (Cell-free assay); Notch (Cell-free assay) 0.5 μM; 2.9 μM(Kd)

Specifications

Sinónimos

Acetic acid,2-​[2-​methoxy-​4-​[(4-​oxo-​2-​thioxo-​5-​thiazolidinylidene)​methyl]​phenoxy]​-

Especificaciones y pureza

≥97%

Mecanismos bioquímicos y fisiológicos

IMR-1A, an acid metabolite of IMR-1, is a potent inhibitor of Notch with IC50 of 0.5 μM and Kd of 2.9 μM. IMR-1A exhibits anti-tumor activity.

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥97%

Propiedades del producto

• ALogP: 2.29
• hba_count: 4
• Recuento HBD: 1
• Enlace rotable: 5

Nombres e identificadores

• Pubchem Sid: 488191798
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488191798
• Sonrisas canónicas: COC1=C(C=CC(=C1)C=C2C(=O)NC(=S)S2)OCC(=O)O
• IUPAC Name: 2-[2-methoxy-4-[(E)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]phenoxy]acetic acid
• InChIKey: DVBJNSKWHSGTDK-BJMVGYQFSA-N
• INCHI: 1S/C13H11NO5S2/c1-18-9-4-7(2-3-8(9)19-6-11(15)16)5-10-12(17)14-13(20)21-10/h2-5H,6H2,1H3,(H,15,16)(H,14,17,20)/b10-5+
• Peso molecular: 325.36
• Reaxy-Rn: 29764446
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=29764446&ln=

Propiedades químicas y físicas

• Solubilidad: Solubility (25°C) In vitro DMSO: 6 mg/mL (18.44 mM); Water: Insoluble; Ethanol: Insoluble
• DMSO (mg/ml) Solubilidad máxima: 6
• DMSO (mM) Solubilidad máxima: 18.4411113843128
• Agua (mg/ml) Solubilidad máxima: ＜1

Preguntas frecuentes

What is the purity of this product?

This product is supplied at ≥97% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 331862-41-0, the molecular formula is C13H11NO5S2, and the molecular weight is 325.36 g/mol. InChIKey DVBJNSKWHSGTDK-BJMVGYQFSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.