Indican - Moligand™, 10 mM in DMSO , CAS No.487-60-5

CAS: 487-60-5 Cat. No.: I1495406 Molecular Weight: 295.29 Beilstein Registry Number: 21(3/4)748 EC Number: 610-433-2

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Indican (Indoxyl-β-D-glucoside), a glycoside of indoxyl, is a precursor of the dyesindigo and indirubin. Indican has a major metabolite, indoxyl sulfate (IS). IS, an uremic toxin, is a substrate/inhibitor of organic anion transporter ( OAT ) 1, OAT 3 and multidrug resistance-associated protein (MRP) 4 .

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Names and Identifiers

• Isomeric SMILES: C1=CC=C2C(=C1)C(=CN2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O
• Molecular Weight: 295.29
• Beilstein: 21(3/4)748
• Reaxy-Rn: 54863578
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=54863578&ln=

Chemical and Physical Properties

• Specific Rotation[α]: -64° (C=2,H2O)
• Melt Point(°C): 183 °C

References

1. Xinyu Zhang, Sufang Li, Tingru Lin, Liangying Gan, Li Zhu, Li Zuo.  (2025)  Pegmolesatide ameliorates indoxyl sulfate-induced cardiomyocyte hypertrophy through modulating the EPOR-CD131-dependent JAK2/STAT3 signaling pathway.  INTERNATIONAL IMMUNOPHARMACOLOGY,      [PMID:41092772] [10.1016/j.intimp.2025.115643]