Integrin beta 3/CD61 Mouse mAb (APC) - Anticuerpo primario, specific to Integrin beta 3

Cat. No.: Ab186829

GRADE & PURITY Validated, ExactAb™, 5 μL/test

Application

Flow Cytometry

Host species

Ratón

Reactive species

Humano

Isotype

Mouse IgG1

Clone Number

HIP11

Conjugation

APC

Descripción general

Mouse anti Human Integrin beta 3/CD61 Antibody, Monoclonal (HIP11), could be used for Flow Cytometry.

Specifications

Product Name

Integrin beta 3/CD61 Mouse mAb (APC) - Anticuerpo primario, specific to Integrin beta 3

Sinónimos

BDPLT16 | BDPLT2 | BDPLT24 | GPIIIa | GT | GT2 | CD61 antigen | CD61 | GP3A | GP3Aplatelet glycoprotein IIIa | GPIIIaintegrin beta-3 | INGRB3 | Integrin beta 3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | ITG B3 | ITGB3 | Platelet membr

Especificaciones y pureza

ExactAb™, Validated, 5 μL/test

Mecanismos bioquímicos y fisiológicos

Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin,

Especies hospedadoras

Ratón

Especificidad

Integrin beta 3

Inmunógeno

Normal peripheral blood platelets and platelets from IPT patients

Control positivo

Flow Cytometry: human peripheral blood platelets

Conjugación

APC

Excitación (nm)

Red Laser(633nm)

Emisión (nm)

660nm

Ex/Em(nm)

Ex:650nm;Em:660nm

Grado

ExactAb™, Validated

Tipo de cadena ligera

kappa

Método de purificación

Protein A purified

Concentración

5 μL/test

Almacenamiento y envío

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C,Protected from light,Do not freeze

Enviado en

Wet ice,Do not freeze

Estabilidad y almacenamiento

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Imágenes

Flow Cytometry: Integrin beta 3/CD61 Mouse mAb (APC) (Ab186829)

Integrin beta 3/CD61 Mouse mAb (APC) (Ab186829) - Flow Cytometry
Flow cytometry analysis of Integrin beta 3/CD61 expression by human peripheral blood platelets (red) compared to an isotype control (blue). Cells were stained with  Integrin beta 3/CD61 Mouse mAb (APC) (Ab186829) at 0.1μg/test for 1 hour at 4°C. Blue - Mouse IgG (APC) (Ab180309). Black - Unlabelled control, cells without incubation with primary antibody.

Aplicación

• Aplicación: Dilution info
• Flow Cytometry:

  5μl/test

  For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood.

Objetivos asociados (humanos)

ITGB3 Tclin Integrin beta-3 (0 Activities)

Discover Target: ITGB3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Preguntas frecuentes

What does ExactAb? mean?

ExactAb? indicates the product has been validated for use in rigorous antibody validation workflows. Validation may include positive/negative control samples, signal-to-noise testing, and protocol-specific QC. Lot-specific test data is published on the Certificate of Analysis where available.

What does Validated mean?

Validated indicates the product has been validated for use in rigorous antibody validation workflows. Validation may include positive/negative control samples, signal-to-noise testing, and protocol-specific QC. Lot-specific test data is published on the Certificate of Analysis where available.

How should this product be stored?

Store at 2–8 °C, protected from light. Do not freeze. Freezing may cause irreversible damage to this material.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (Integrin beta 3/CD61 Mouse mAb (APC)); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.