IQ-1S - 10mM in DMSO , CAS No.23146-22-7

CAS: 23146-22-7 Cat. No.: I422742 Fórmula: C₁₅H₉N₃O Peso molecular: 247.25 PubChem CID: 619002

GRADE & PURITY 10mM in DMSO

Synonyms

11H-Indeno[1,2-b]quinoxalin-11-oneoxime

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Store at Room Temperature. The product can be stored for up to 12 months.

Specifications

Sinónimos

11H-Indeno[1,2-b]quinoxalin-11-oneoxime

Especificaciones y pureza

10mM in DMSO

Mecanismos bioquímicos y fisiológicos

Selective JNK3 inhibitor (IC 50 values are 390, 360 and 87 nM for JNK1, 2 and 3 respectively). Inhibits JNK phosphorylation and NFκB /AP-1 transcriptional activity. Shows immunosuppressant effects in vivo.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Nombres e identificadores

Pubchem Sid

528764906

Sonrisas canónicas

C1=CC=C2C(=C1)C(=C3C2=NC4=CC=CC=C4N3)N=O

IUPAC Name

11-nitroso-10H-indeno[1,2-b]quinoxaline

InChIKey

YSYIWCNPSZNNKW-UHFFFAOYSA-N

INCHI

1S/C15H9N3O/c19-18-14-10-6-2-1-5-9(10)13-15(14)17-12-8-4-3-7-11(12)16-13/h1-8,17H

Isómeros SMILES

C1=CC=C2C(=C1)C(=C3C2=NC4=CC=CC=C4N3)N=O

PubChem CID

619002

Peso molecular

247.25

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Diazanaphthalenes
      • Subclass Benzodiazines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Diazanaphthalenes
• Subclass: Benzodiazines
• Intermediate Tree Nodes: Not available
• Direct Parent: Quinoxalines
• Alternative Parents: Pyrazines Benzenoids Heteroaromatic compounds Propargyl-type 1,3-dipolar organic compounds C-nitroso compounds Azacyclic compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Quinoxaline - Pyrazine - Benzenoid - Heteroaromatic compound - C-nitroso compound - Organic nitroso compound - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Azacycle - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organic oxide - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as quinoxalines. These are compounds containing a quinoxaline moiety, a bicyclic heterocycle made up of a benzene ring fused to a pyrazine ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Sensibilidad: Moisture Sensitive
• Punto de fusión (°C): 262 °C
• Peso molecular: 247.250 g/mol
• XLogP3: 2.700
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 247.075 Da
• Monoisotopic Mass: 247.075 Da
• Topological Polar Surface Area: 58.100 Ų
• Heavy Atom Count: 19
• Formal Charge: 0
• Complexity: 361.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1