IRF4 Mouse mAb - Anticuerpo primario, specific to IRF4, Mouse IgG

Cat. No.: Ab116479

GRADE & PURITY Carrier Free, Validated, ExactAb™, Azide Free, 1.0 mg/mL

Application

IHC

Host species

Ratón

Reactive species

Humano

Isotype

Mouse IgG

Clone Number

YN02156m

Conjugation

Unconjugated

Descripción general

Mouse anti Human IRF4 Antibody, Monoclonal (YN02156m), could be used for IHC and so on.
Application
IHC: 1/400
Protein Function
Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes.

Specifications

Product Name

IRF4 Mouse mAb - Anticuerpo primario, specific to IRF4, Mouse IgG

Sinónimos

IRF 4 antibody | IRF-4 antibody | Irf4 antibody | IRF4_HUMAN antibody | LSIRF antibody | Lymphocyte specific interferon regulatory factor antibody | Lymphocyte specific IRF antibody | Lymphocyte-specific interferon regulatory factor antibody | Interferon

Especificaciones y pureza

ExactAb™, Validated, Carrier Free, Azide Free, 1.0 mg/mL

Especies hospedadoras

Ratón

Especificidad

IRF4

Inmunógeno

Peptide

Control positivo

IHC: Human tonsil tissue.

Conjugación

Unconjugated

Grado

Azide Free, Carrier Free, ExactAb™, Validated

Isotipo

Mouse IgG

Tipo de cadena ligera

kappa

SDS-PAGE

150 kDa

Método de purificación

Protein G purified

Concentración

1.0 mg/mL

Almacenamiento y envío

Forma

Liquid

Condiciones de almacenamiento de almacenamiento

Store at -20°C,Avoid repeated freezing and thawing

Enviado en

Ice chest + Ice pads

Estabilidad y almacenamiento

Store at -20℃ long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Imágenes

IHC: IRF4 Mouse mAb (Ab116479)

IRF4 Mouse mAb (Ab116479) - IHC
Immunohistochemistry analysis of paraffin-embedded human tonsil tissue labelling IRF4 with IRF4 Mouse mAb (Ab116479) at 1/400 dilution. The section was incubated with IRF4 Mouse mAb (Ab116479) ​for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.​

Aplicación

• Aplicación: Dilution info
• IHC:

  1/400

Objetivos asociados (humanos)

IRF4 Tbio Interferon regulatory factor 4 (0 Activities)

Discover Target: IRF4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Preguntas frecuentes

What does ExactAb? mean?

ExactAb? indicates the product has been validated for use in rigorous antibody validation workflows. Validation may include positive/negative control samples, signal-to-noise testing, and protocol-specific QC. Lot-specific test data is published on the Certificate of Analysis where available.

What does Carrier Free mean?

Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

How should this product be stored?

Store at ?20 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (IRF4 Mouse mAb); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.