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for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
L 858051 is an analog of forskolin that activates adenylate cyclase while also having modulatory effects on intracellular cAMP levels, particularly enhancing the CNG current in cardiac myocytes.
| Canonical Smiles | CC1(CCC(C2(C1C(C(C3(C2(C(=O)CC(O3)(C)C=C)O)C)OC(=O)CCCN4CCN(CC4)C)O)C)O)C |
|---|---|
| IUPAC Name | [(3R,4aS,5R,6R,6aR,10R,10aS,10bR)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] 4-(4-methylpiperazin-1-yl)butanoate |
| InChIKey | PAYHDZDDAHVPDU-AFGWWSASSA-N |
| INCHI | 1S/C29H48N2O7/c1-8-26(4)18-20(33)29(36)27(5)19(32)11-12-25(2,3)23(27)22(35)24(28(29,6)38-26)37-21(34)10-9-13-31-16-14-30(7)15-17-31/h8,19,22-24,32,35-36H,1,9-18H2,2-7H3/t19-,22-,23-,24-,26+,27-,28+,29-/m1/s1 |
| Isomeric SMILES | C[C@@]1(CC(=O)[C@]2([C@@]3([C@@H](CCC([C@H]3[C@H]([C@H]([C@@]2(O1)C)OC(=O)CCCN4CCN(CC4)C)O)(C)C)O)C)O)C=C |
| Alternate CAS | 110452-75-0 |
| PubChem CID | 130638 |
| MeSH Entry Terms | 7-beta-(gamma-(N'-methylpiperazino)-butyryloxy)-7-desacetylforskolin;7-desacetyl-7-(gamma-N-methylpiperazino)butyrylforskolin;7-MPB-forskolin;7B-forskolin;DMPB-forskolin;L 858051;L-858051;L858051 |
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