L-AP3 - ≥97% , CAS No.23052-80-4

CAS: 23052-80-4 Cat. No.: L338646 Fórmula: C₃H₈NO₅P Peso molecular: 169.07 Beilstein Registry Number: 3649605 Número EC: 630-752-0

GRADE & PURITY ≥97%

Synonyms

DTXSID501017380 | NCGC00097437-01 | NSC 133887 | 2-(r)-amino-3-phosphonopropionic acid | L-Alanine, 3-phosphono- | L-(+)-2-Amino-3-phosphonopropionic acid | l(+)-2-amino-3-phosphonopropionic acid | l-ap3 | DL-2-Amino-3-phosphonopropionic acid (AP3) | HY-1

Storage

Store at 2-8°C

Shipped In

Wet ice

Descripción general

L-AP3 is a selective antagonist of the PI-linked metabotropic glutamate response.

Specifications

Sinónimos

DTXSID501017380 | NCGC00097437-01 | NSC 133887 | 2-(r)-amino-3-phosphonopropionic acid | L-Alanine, 3-phosphono- | L-(+)-2-Amino-3-phosphonopropionic acid | l(+)-2-amino-3-phosphonopropionic acid | l-ap3 | DL-2-Amino-3-phosphonopropionic acid (AP3) | HY-1

Especificaciones y pureza

≥97%

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

ANTAGONIST

Pureza

≥97%

Propiedades del producto

• pKa: pKa: 1.22 (Predicted), pKa: 9.54 (Predicted)

Nombres e identificadores

• Sonrisas canónicas: C(C(C(=O)O)N)P(=O)(O)O
• IUPAC Name: (2R)-2-amino-3-phosphonopropanoic acid
• InChIKey: LBTABPSJONFLPO-REOHCLBHSA-N
• INCHI: 1S/C3H8NO5P/c4-2(3(5)6)1-10(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)/t2-/m0/s1
• Isómeros SMILES: C([C@@H](C(=O)O)N)P(=O)(O)O
• WGK Alemania: 3
• Peso molecular: 169.07
• Beilstein: 3649605
• Reaxy-Rn: 2253277
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2253277&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Alpha amino acids
              • Level8 L-alpha-amino acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids
• Direct Parent: L-alpha-amino acids
• Alternative Parents: Organic phosphonic acids Amino acids Monocarboxylic acids and derivatives Carboxylic acids Organopnictogen compounds Organophosphorus compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: L-alpha-amino acid - Organophosphonic acid - Organophosphonic acid derivative - Amino acid - Carboxylic acid - Monocarboxylic acid or derivatives - Amine - Hydrocarbon derivative - Primary amine - Organophosphorus compound - Organooxygen compound - Organonitrogen compound - Organic oxide - Organopnictogen compound - Organic oxygen compound - Primary aliphatic amine - Organic nitrogen compound - Carbonyl group - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)

Discover Target: CYP2D6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)

Discover Target: CYP1A2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)

Discover Target: CYP2C9

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)

Discover Target: CYP2C19

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: Soluble in water.
• Índice de refracción: n20D1.56 (Predicted)
• Punto de ebullición (°C): 481.62° C at 760 mmHg (Predicted)
• Punto de fusión (°C): 227-229° C
• Peso molecular: 169.070 g/mol
• XLogP3: -5.200
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 169.014 Da
• Monoisotopic Mass: 169.014 Da
• Topological Polar Surface Area: 121.000 Ų
• Heavy Atom Count: 10
• Formal Charge: 0
• Complexity: 174.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Preguntas frecuentes

What is the purity of this product?

This product is supplied at ≥97% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at 2–8 °C. Refrigerated storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 23052-80-4, the molecular formula is C3H8NO5P, and the molecular weight is 169.07 g/mol. InChIKey LBTABPSJONFLPO-REOHCLBHSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.