L-Cycloserine - Moligand™, 10mM in DMSO , CAS No.339-72-0
Disponible
SKU
L423473
L-Cycloserine is an irreversible inhibitor of 3-ketodihydrosphingosine synthetase, which is the first enzyme of the sphingolipid pathway, and causes the synthesis of sphingolipids to decrease. In vitro studies demonstrated that L-cyloserine inhibits 3-ketodihydrosphingosine synthetase 100 times more than D-Cycloserine .Research regarding L-Cycloserine and its effect on the immune response suggest that L-Cycloserine increases the level of IL-4 producing helper T cells and suppress the adhesion molecules CD29 and CD98. L-Cycloserine also inhibits SPTLC (serine palmitoyltransferase (SPT)), and HIV-1 investigations in the CD4+ lymphoid cell line (CEM) have shown that L-Cycloserine can inhibit HIV-1 replication.
An irreversible inhibitor of 3-ketodihydrosphingosine synthetase
Más Información
| CAS | 339-72-0 |
|---|---|
| Concentración | 10mM in DMSO |
| Sinónimos | (-)-4-amino-3-isoxazolidinone | Levcicloserina [INN-Spanish] | LEVCYCLOSERINE [INN] | L-Oxamicina [Italian] | BSPBio_001132 | MFCD00064324 | 4AX | Prestwick1_001086 | (4S)-4-amino-1,2-oxazolidin-3-one | HMS3264E06 | LP00199 | NCGC00093674-01 | NCGC0009367 |
| Especificaciones y pureza | Moligand™, 10mM in DMSO |
| Condiciones de almacenamiento de almacenamiento | Store at -80°C |
| Enviado en | Dry ice packs + Cold packs |
| Product Description | L-Cycloserine is an irreversible inhibitor of 3-ketodihydrosphingosine synthetase, which is the first enzyme of the sphingolipid pathway, and causes the synthesis of sphingolipids to decrease. In vitro studies demonstrated that L-cyloserine inhibits 3-ketodihydrosphingosine synthetase 100 times more than D-Cycloserine .Research regarding L-Cycloserine and its effect on the immune response suggest that L-Cycloserine increases the level of IL-4 producing helper T cells and suppress the adhesion molecules CD29 and CD98. L-Cycloserine also inhibits SPTLC (serine palmitoyltransferase (SPT)), and HIV-1 investigations in the CD4+ lymphoid cell line (CEM) have shown that L-Cycloserine can inhibit HIV-1 replication. |
| Pubchem Sid | 528765185 |
| Número CE | 206-427-0 |
| PubChem CID | 449215 |
| Fórmula molecular | C3H6N2O2 |
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