L-Cystine - Moligand™, analytical standard, ≥99.5% , CAS No.56-89-3

CAS: 56-89-3 Cat. No.: C108226 Fórmula: C₆H₁₂N₂O₄S₂ Peso molecular: 240.3 Beilstein Registry Number: 1728094 Número EC: 200-296-3

GRADE & PURITY Analytical standard, Moligand™, ≥99.5%

Synonyms

L-CYSTINE | b,b'-Dithiodialanine | CYSTINE (EP MONOGRAPH) | (R,R)-3,3'-dithiobis(2-aminopropanoic acid) | CYSTINE [INN] | Cystine [USAN] | CYSTINE [WHO-DD] | L-alpha-Diamino-beta-dithiolactic acid | L-CYSTINE [JAN] | L-Cystine, non-animal source | S-CYSTE

Storage

Protected from light,Desiccated,Room temperature

Shipped In

Normal

Descripción general

A non-essential amino acid vital for human development

Specifications

Sinónimos

L-CYSTINE | b,b'-Dithiodialanine | CYSTINE (EP MONOGRAPH) | (R,R)-3,3'-dithiobis(2-aminopropanoic acid) | CYSTINE [INN] | Cystine [USAN] | CYSTINE [WHO-DD] | L-alpha-Diamino-beta-dithiolactic acid | L-CYSTINE [JAN] | L-Cystine, non-animal source | S-CYSTE

Especificaciones y pureza

Moligand™, analytical standard, ≥99.5%

Mecanismos bioquímicos y fisiológicos

L-Cystine is a non-essential amino acid vital for human development formed by the dimerization of two cysteines. Its derivatives act as ligands for neuronal nicotine receptors and have various pharmacological activities.

Condiciones de almacenamiento de almacenamiento

Protected from light,Desiccated,Room temperature

Enviado en

Normal

Grado

Moligand™, Patrón analítico

Pureza

≥99.5%

Nombres e identificadores

Pubchem Sid

528765218

Sonrisas canónicas

C([C@@H](C(=O)O)N)SSC[C@@H](C(=O)O)N

IUPAC Name

(2R)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]disulfanyl]propanoic acid

InChIKey

LEVWYRKDKASIDU-IMJSIDKUSA-N

INCHI

1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1

Isómeros SMILES

C([C@@H](C(=O)O)N)SSC[C@@H](C(=O)O)N

WGK Alemania

3

Peso molecular

240.3

Beilstein

1728094

Reaxy-Rn

1728094

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1728094&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Cysteine and derivatives
              • Level8 L-cysteine-S-conjugates

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives - Cysteine and derivatives
• Direct Parent: L-cysteine-S-conjugates
• Alternative Parents: L-alpha-amino acids Dicarboxylic acids and derivatives Dialkyldisulfides Amino acids Sulfenyl compounds Carboxylic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: L-cysteine-s-conjugate - Alpha-amino acid - L-alpha-amino acid - Dicarboxylic acid or derivatives - Organic disulfide - Dialkyldisulfide - Amino acid - Sulfenyl compound - Carboxylic acid - Organopnictogen compound - Organic nitrogen compound - Primary amine - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Organic oxygen compound - Carbonyl group - Hydrocarbon derivative - Amine - Organic oxide - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as l-cysteine-s-conjugates. These are compounds containing L-cysteine where the thio-group is conjugated.
• External Descriptors: non-proteinogenic L-alpha-amino acid - L-cysteine derivative - cystine

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

F2 Tclin Thrombin (11687 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ESR1 Tclin Estrogen receptor alpha (17718 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PGR Tclin Progesterone receptor (8562 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)

Discover Target: CHRM2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)

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AR Tclin Androgen Receptor (11781 Activities)

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CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GABRA1 Tclin GABA receptor alpha-1 subunit (399 Activities)

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MAOA Tclin Monoamine oxidase A (11911 Activities)

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DRD1 Tclin Dopamine D1 receptor (9720 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ACHE Tclin Acetylcholinesterase (18204 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A2 Tclin Norepinephrine transporter (10102 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A4 Tclin Serotonin transporter (12625 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)

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OPRM1 Tclin Mu opioid receptor (19785 Activities)

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DRD3 Tclin Dopamine D3 receptor (14368 Activities)

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SLC6A3 Tclin Dopamine transporter (10535 Activities)

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PDE3A Tclin Phosphodiesterase 3A (3309 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TBXA2R Tclin Thromboxane A2 receptor (5717 Activities)

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PDE4A Tclin Phosphodiesterase 4A (1943 Activities)

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ADORA3 Tchem Adenosine A3 receptor (15931 Activities)

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HRH3 Tclin Histamine H3 receptor (10389 Activities)

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POLK Tbio DNA polymerase kappa (8653 Activities)

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Objetivos asociados (no humanos)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: Soluble in dilute acid and alkali solutions, extremely insoluble in water, insoluble in ethanol.
• Sensibilidad: Light sensitive.
• Rotación específica [α]: -222.5 ° (C=1, 1mol/L HCl)
• Punto de fusión (°C): 260-261°C
• Peso molecular: 240.300 g/mol
• XLogP3: -6.300
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 7
• Exact Mass: 240.024 Da
• Monoisotopic Mass: 240.024 Da
• Topological Polar Surface Area: 177.000 Ų
• Heavy Atom Count: 14
• Formal Charge: 0
• Complexity: 192.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1