α-Lactose monohydrate - analytical standard , CAS No.5989-81-1

CAS: 5989-81-1 Cat. No.: L102284 Fórmula: C₁₂H₂₂O₁₁ · H₂O Peso molecular: 360.31 Número EC: 611-913-4

GRADE & PURITY Analytical standard

Synonyms

alpha-Lactose monohydrate | Respitose | Fenyramidol (VAN) (*hydrochloride*) | Lactose monohydrate | .alpha.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-, monohydrate | Lactose (JP17) | Spherolac 100 | LACTOSE MONOHYDRATE [EP MONOGRAPH] | (2R,3R,4S,5R,6

Storage

Room temperature

Shipped In

Normal

Specifications

Sinónimos

alpha-Lactose monohydrate | Respitose | Fenyramidol (VAN) (*hydrochloride*) | Lactose monohydrate | .alpha.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-, monohydrate | Lactose (JP17) | Spherolac 100 | LACTOSE MONOHYDRATE [EP MONOGRAPH] | (2R,3R,4S,5R,6

Especificaciones y pureza

analytical standard

Condiciones de almacenamiento de almacenamiento

Room temperature

Enviado en

Normal

Grado

Patrón analítico

Nombres e identificadores

• Pubchem Sid: 508811267
• Sonrisas canónicas: C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)O)CO)O)O)O)O.O
• IUPAC Name: (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol;hydrate
• InChIKey: WSVLPVUVIUVCRA-KPKNDVKVSA-N
• INCHI: 1S/C12H22O11.H2O/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17;/h3-20H,1-2H2;1H2/t3-,4-,5+,6+,7-,8-,9-,10-,11+,12+;/m1./s1
• Isómeros SMILES: C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)O)CO)O)O)O)O.O
• CAS alternativo: 14641-93-1
• Peso molecular: 360.31
• Reaxy-Rn: 38095197
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=38095197&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Clase Organooxygen compounds
      • Subclass Carbohydrates and carbohydrate conjugates
        • Level5 Glycosyl compounds
          • Level6 O-glycosyl compounds

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Clase: Organooxygen compounds
• Subclass: Carbohydrates and carbohydrate conjugates
• Intermediate Tree Nodes: Glycosyl compounds
• Direct Parent: O-glycosyl compounds
• Alternative Parents: Disaccharides Oxanes Secondary alcohols Hemiacetals Polyols Oxacyclic compounds Acetals Primary alcohols Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: O-glycosyl compound - Disaccharide - Oxane - Secondary alcohol - Hemiacetal - Oxacycle - Organoheterocyclic compound - Polyol - Acetal - Organic oxide - Hydrocarbon derivative - Primary alcohol - Alcohol - Aliphatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as o-glycosyl compounds. These are glycoside in which a sugar group is bonded through one carbon to another group via a O-glycosidic bond.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Rotación específica [α]: 54.4° (c=10, H2O, NH3)
• Punto de fusión (°C): 219°C
• Peso molecular: 360.310 g/mol
• Hydrogen Bond Donor Count: 9
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 4
• Exact Mass: 360.127 Da
• Monoisotopic Mass: 360.127 Da
• Topological Polar Surface Area: 191.000 Ų
• Heavy Atom Count: 24
• Formal Charge: 0
• Complexity: 382.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 10
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

Referencias

1. Zheng Jiang, Hong Wang, Miao Yu, Cheng Qu, Wei Yue, Qinan Wu.  (2023)  A low-cost efficient online derivatization system for the determination of saccharides by high-performance liquid chromatograph-ultraviolet detector.  JOURNAL OF SEPARATION SCIENCE,  46  (20): (2300384).  [PMID:37691057] [10.1002/jssc.202300384]

2. Haiqing Wang, Wei Shi, Lei Hou, Chunhui Li, Zhiquan Wang, Lei Yang, Juncheng Cao.  (2022)  Quantitative analysis of aqueous biomolecular mixtures by THz spectroscopy based on high-power LiNbO3 radiation source.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:36356399] [10.1016/j.saa.2022.122075]

3. Yuqi Yang, Yiyue Guo, You Xu, Yingying Meng, Xing Zhang, Xuejun Xia, YuLing Liu.  (2020)  Factors affecting the buccal delivery of deformable nanovesicles based on insulin–phospholipid complex: an in vivo investigation.  DRUG DELIVERY,      [PMID:32597266] [10.1080/10717544.2020.1778814]

4. You Xu, Yiyue Guo, Yuqi Yang, Yingying Meng, Xuejun Xia, Yuling Liu.  (2019)  Stabilization of Deformable Nanovesicles Based on Insulin-Phospholipid Complex by Freeze-Drying.  Pharmaceutics,  11  (10): (539).  [PMID:31623287] [10.3390/pharmaceutics11100539]

5. Rui Li, Jinhu Wang, Yi He, Faqin Dong, Liang Bian, Bowen Li.  (2019)  Mechanochemical Synthesis of Defective Molybdenum Trioxide, Titanium Dioxide, and Zinc Oxide at Room Temperature.  ACS Sustainable Chemistry & Engineering,      [PMID:] [10.1021/acssuschemeng.9b00374]

6. Jin-Wen Liu, Tingting Chen, Meiqun Cai, Yingfeng Qin, Mei Li.  (2024)  A Dual-Mode Optical Sensing Strategy for Rapid Detection of D-Penicillamine in Pharmaceutical Formulations.  ANALYTICAL LETTERS,      [PMID:] [10.1080/00032719.2024.2419533]

7. Changmao Yang, Yue Xiao, Yunjun Yan, Houjin Zhang.  (2024)  A xylenol orange-based pH-sensitive sensor array for identification of bacteria and differentiation of probiotic drinks.  Analytical Methods,      [PMID:39655744] [10.1039/D4AY01982B]

8. Ping Chen, Hui Zhong, Xiao-rong Li, Tingting Zhang, Xiang Wang, Fang Hu, Yubo Yan, Jiaxing Xu, Meisheng Li.  (2024)  Copper-ion-complexed palygorskite as a novel nanozyme with enhanced peroxidase-like activity for sensitive colorimetric sensing.  APPLIED CLAY SCIENCE,      [PMID:] [10.1016/j.clay.2024.107507]

9. Wei Cheng, Huilin Wen, Haixia Shen, Chenwei Fu, Erkuang Miao, Dongbao Li, Xiaoqiang Chen, Chi Hu, Ziyi Yu.  (2024)  Enzyme induced polymer degradation as a pathway to create microbial habitats for biomanufacturing intensification.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.153622]

10. Xiaokang Tian, Rongrong Fan, Wenyi Wei, Dan Wang, Yuan Le, Jian-Feng Chen.  (2025)  Water-Based Nanoparticulate Formulation of Lambda-Cyhalothrin and Its Enhancement of Bioavailability.  LANGMUIR,      [PMID:40884502] [10.1021/acs.langmuir.5c02947]

11. Binggang Xiao, Yichun Wang, Xiuran Zuo, Luqi Liu, Jianyuan Qin, Wanshun Jiang, Yumei Zhang, Lihua Xiao.  (2025)  Dual-band terahertz metasurface biosensor based on electromagnetically induced transparency effects for antibiotic detection.  OPTICS AND LASERS IN ENGINEERING,      [PMID:] [10.1016/j.optlaseng.2025.109305]

12. Fang Wang, Yi-Mei Li, Jing Zhao, Jing Ye, Yuan-Ting Li.  (2025)  Visualized molecularly-imprinted hydrogel chips for point-of-care SERS assay of N-nitrosodiethylamine contamination in antihypertensive drugs.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2025.115285]

13. Liang Zhang, Haifeng Lu, Xiaolei Guo, Haifeng Liu.  (2026)  Micro-feeding and mixing of pharmaceutical solid dosage forms under external vibration.  CHEMICAL ENGINEERING RESEARCH & DESIGN,      [PMID:] [10.1016/j.cherd.2026.01.048]

14. Junnan Wang, Lei Hou, Yusong Zhang, Lei Yang, Wei Shi.  (2026)  Quantitative detection of substances without feature absorption peak by terahertz Rydberg atom sensor.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:] [10.1016/j.saa.2026.127825]

15. Lianfeng Liu, Turghun Muhammad, Jia Zhao, Feiyu Zhan, Yan Zhang.  (2026)  Centrifugation Assisted Two-Phase Hollow-Fiber Liquid-Phase Microextraction Coupled With Direct Fluorimetry for Precise Thiamine Detection.  Separation Science Plus,  9  (3): (e70209).  [PMID:] [10.1002/sscp.70209]

16. Mengyue Gao, Zhiheng Li, Mengjie Liu, Ting He, Xiaolu Su, Yueting Zhao, Zhiqiao Zou, Yanxing Yao, Fengmei Jin, Zhihao Li, Lihua Wang.  (2026)  Dual-metal-site MOF nanozyme with enhanced activity for highly sensitive colorimetric detection of Cr(VI) in dairy products.  FOOD CHEMISTRY,      [PMID:42475989] [10.1016/j.foodchem.2026.150463]