Immunology/Inflammation - Sistema del complemento Supplier | High Purity

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Avacopan (CCX168), Antagonist of C5a 1 receptor
CAS: 1346623-17-3 Número EC: 877-511-8 Fórmula: C₃₃H₃₅F₄N₃O₂ Peso molecular: 581.64

Moligand™ ? 10mM in DMSO

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: A421311
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Nombre IUPAC

(2R,3S)-2-[4-(cyclopentylamino)phenyl]-1-(2-fluoro-6-methylbenzoyl)-N-[4-methyl-3-(trifluoromethyl)phenyl]piperidine-3-carboxamide

SMILES

CC1=C(C(=CC=C1)F)C(=O)N2CCCC(C2C3=CC=C(C=C3)NC4CCCC4)C(=O)NC5=CC(=C(C=C5)C)C(F)(F)F

InChIKey
PUKBOVABABRILL-YZNIXAGQSA-N

InChI

1S/C33H35F4N3O2/c1-20-12-15-25(19-27(20)33(35,36)37)39-31(41)26-10-6-18-40(32(42)29-21(2)7-5-11-28(29)34)30(26)22-13-16-24(17-14-22)38-23-8-3-4-9-23/hshow more

Sinónimos
(2R,3S)-2-[4-(Cyclopentylamino)phenyl]-1-(2-fluoro-6-methylbenzoyl)-N-[4-methyl-3-(trifluoromethyl)phenyl]-3-piperidi...
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Compstatin TFA
CAS: 206645-99-0 Fórmula: C₆₆H₉₉N₂₃O₁₇S₂.xC₂HF₃O₂ Peso molecular: 1550.77（free basis）

Solid Moligand™ ? ≥98%

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Nombre IUPAC

2-[(4R,7S,10S,13S,19S,22S,25S,28S,31S,34R)-4-[[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]carbamoyl]-34-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]-25-(show more

SMILES

CCC(C)C(C(=O)NC1CSSCC(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)C(C)C)C(C)C)CCC(=O)N)CC(=O)O)CC2=CNC3=CC=CC=C32)CC4show more

InChIKey
RDTRHBCZFDCUPW-KWICJJCGSA-N

InChI

1S/C66H99N23O17S2/c1-8-32(6)50(68)63(104)86-46-27-108-107-26-45(62(103)89-53(33(7)90)54(69)95)85-56(97)39(14-11-17-74-66(70)71)80-59(100)43(20-36-24-7show more

Sinónimos
2-((4R,7S,10S,13S,19S,22S,25S,28S,31S,34R)-10,13-Bis((1H-imidazol-4-yl)methyl)-19-((1H-indol-3-yl)methyl)-4-(((2S,3R)...
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Danicopan (ACH-4471), Complement factor D inhibitor
CAS: 1903768-17-1 Fórmula: C₂₆H₂₃BrFN₇O₃ Peso molecular: 580.41

Solid Moligand™ ? ≥98%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: D412556
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Nombre IUPAC

(2S,4R)-1-[2-[3-acetyl-5-(2-methylpyrimidin-5-yl)indazol-1-yl]acetyl]-N-(6-bromopyridin-2-yl)-4-fluoropyrrolidine-2-carboxamide

SMILES

CC1=NC=C(C=N1)C2=CC3=C(C=C2)N(N=C3C(=O)C)CC(=O)N4CC(CC4C(=O)NC5=NC(=CC=C5)Br)F

InChIKey
PIBARDGJJAGJAJ-NQIIRXRSSA-N

InChI

1S/C26H23BrFN7O3/c1-14(36)25-19-8-16(17-10-29-15(2)30-11-17)6-7-20(19)35(33-25)13-24(37)34-12-18(28)9-21(34)26(38)32-23-5-3-4-22(27)31-23/h3-8,10-11,1show more

Sinónimos
BDBM354268 | JM8C1SFX0U | DANICOPAN [JAN] | 1903768-17-1 | MLS006011963 | Danicopan free base | MS-30411 | (2S,4R)-1-...
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EG 00229 trifluoroacetate
CAS: 1210945-69-9 PubChem CID: 45142253 Fórmula: C₁₇H₁₉N₇O₅S₃.CF₃CO₂H Peso molecular: 611.59

≥98%(HPLC)

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: E287676
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Nombre IUPAC

(2S)-2-[[3-(2,1,3-benzothiadiazol-4-ylsulfonylamino)thiophene-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid;2,2,2-trifluoroacetic acid

SMILES

C1=CC2=NSN=C2C(=C1)S(=O)(=O)NC3=C(SC=C3)C(=O)NC(CCCN=C(N)N)C(=O)O.C(=O)(C(F)(F)F)O

InChIKey
ZYQBITUOSRZDTG-MERQFXBCSA-N

InChI

1S/C17H19N7O5S3.C2HF3O2/c18-17(19)20-7-2-4-11(16(26)27)21-15(25)14-10(6-8-30-14)24-32(28,29)12-5-1-3-9-13(12)23-31-22-9;3-2(4,5)1(6)7/h1,3,5-6,8,11,24show more

Sinónimos
N2-[[3-[(2,1,3-Benzothiadiazol-4-ylsulfonyl)amino]-2-thienyl]carbonyl]-L-arginine trifluoroacetate
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Leukadherin-1
CAS: 344897-95-6 Fórmula: C₂₂H₁₅NO₄S₂ Peso molecular: 421.49

10mM in DMSO

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Nombre IUPAC

4-[5-[(Z)-(3-benzyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl]benzoic acid

SMILES

C1=CC=C(C=C1)CN2C(=O)C(=CC3=CC=C(O3)C4=CC=C(C=C4)C(=O)O)SC2=S

InChIKey
AEZGRQSLKVNPCI-UNOMPAQXSA-N

InChI

1S/C22H15NO4S2/c24-20-19(29-22(28)23(20)13-14-4-2-1-3-5-14)12-17-10-11-18(27-17)15-6-8-16(9-7-15)21(25)26/h1-12H,13H2,(H,25,26)/b19-12-

Sinónimos
Leukadherin 1 | SCHEMBL18301010 | HY-15701 | (Z)-4-(5-((3-benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-y...
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PMX 53
CAS: 219639-75-5 PubChem CID: 6918468 Fórmula: C₄₇H₆₅N₁₁O₇ Peso molecular: 896.1

Moligand™ ? 10mM in DMSO

◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: P422637
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Nombre IUPAC

(2S)-2-acetamido-N-[(3S,9S,12S,15R,18S)-15-(cyclohexylmethyl)-9-[3-(diaminomethylideneamino)propyl]-12-(1H-indol-3-ylmethyl)-2,8,11,14,17-pentaoxo-1,7show more

SMILES

CC(=O)NC(CC1=CC=CC=C1)C(=O)NC2CCCNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C3CCCN3C2=O)CC4CCCCC4)CC5=CNC6=CC=CC=C65)CCCN=C(N)N

InChIKey
YOKBGCTZYPOSQM-HPSWDUTRSA-N

InChI

1S/C47H65N11O7/c1-29(59)53-37(25-30-13-4-2-5-14-30)42(61)55-36-20-11-22-50-41(60)35(19-10-23-51-47(48)49)54-44(63)39(27-32-28-52-34-18-9-8-17-33(32)34show more
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Phaseoloidin
CAS: 118555-82-1 PubChem CID: 14104237 Fórmula: C₁₄H₁₈O₉ Peso molecular: 330.29

≥98%

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Nombre IUPAC

2-[5-hydroxy-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]acetic acid

SMILES

C1=CC(=C(C=C1O)CC(=O)O)OC2C(C(C(C(O2)CO)O)O)O

InChIKey
MVFYXXNAFZRZAM-RGCYKPLRSA-N

InChI

1S/C14H18O9/c15-5-9-11(19)12(20)13(21)14(23-9)22-8-2-1-7(16)3-6(8)4-10(17)18/h1-3,9,11-16,19-21H,4-5H2,(H,17,18)/t9-,11-,12+,13-,14-/m1/s1

Sinónimos
AKOS040758809 | MS-24951 | HY-N7400 | PHASEOLOIDIN | s3240 | [2-(beta-D-Glucopyranosyloxy)-5-hydroxyphenyl]acetic aci...
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Phaseoloidin
CAS: 118555-82-1 PubChem CID: 14104237 Fórmula: C₁₄H₁₈O₉ Peso molecular: 330.29

10mM in DMSO

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: P420816
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Nombre IUPAC

2-[5-hydroxy-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]acetic acid

SMILES

C1=CC(=C(C=C1O)CC(=O)O)OC2C(C(C(C(O2)CO)O)O)O

InChIKey
MVFYXXNAFZRZAM-RGCYKPLRSA-N

InChI

1S/C14H18O9/c15-5-9-11(19)12(20)13(21)14(23-9)22-8-2-1-7(16)3-6(8)4-10(17)18/h1-3,9,11-16,19-21H,4-5H2,(H,17,18)/t9-,11-,12+,13-,14-/m1/s1

Sinónimos
AKOS040758809 | MS-24951 | HY-N7400 | PHASEOLOIDIN | s3240 | [2-(beta-D-Glucopyranosyloxy)-5-hydroxyphenyl]acetic aci...
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SB 290157 trifluoroacetate
CAS: 1140525-25-2 PubChem CID: 16760645 Fórmula: C₂₄H₂₉F₃N₄O₆ Peso molecular: 526.51

≥97%(HPLC)

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: S287899
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Nombre IUPAC

(2S)-5-(diaminomethylideneamino)-2-[[2-(2,2-diphenylethoxy)acetyl]amino]pentanoic acid;2,2,2-trifluoroacetic acid

SMILES

C1=CC=C(C=C1)C(COCC(=O)NC(CCCN=C(N)N)C(=O)O)C2=CC=CC=C2.C(=O)(C(F)(F)F)O

InChIKey
ZJRMPPVJAQWGEG-FYZYNONXSA-N

InChI

1S/C22H28N4O4.C2HF3O2/c23-22(24)25-13-7-12-19(21(28)29)26-20(27)15-30-14-18(16-8-3-1-4-9-16)17-10-5-2-6-11-17;3-2(4,5)1(6)7/h1-6,8-11,18-19H,7,12-15H2show more

Sinónimos
N2-[2-(2,2-Diphenylethoxy)acetyl]-L-arginine trifluoroacetate | N2-[2-(2,2-diphenylethoxy)acetyl]-L-arginine, 2,2,2-t...
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SB 290157 trifluoroacetate
CAS: 1140525-25-2 PubChem CID: 16760645 Fórmula: C₂₄H₂₉F₃N₄O₆ Peso molecular: 526.51

10mM in DMSO

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: S420706
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Identificadores técnicos

Nombre IUPAC

(2S)-5-(diaminomethylideneamino)-2-[[2-(2,2-diphenylethoxy)acetyl]amino]pentanoic acid;2,2,2-trifluoroacetic acid

SMILES

C1=CC=C(C=C1)C(COCC(=O)NC(CCCN=C(N)N)C(=O)O)C2=CC=CC=C2.C(=O)(C(F)(F)F)O

InChIKey
ZJRMPPVJAQWGEG-FYZYNONXSA-N

InChI

1S/C22H28N4O4.C2HF3O2/c23-22(24)25-13-7-12-19(21(28)29)26-20(27)15-30-14-18(16-8-3-1-4-9-16)17-10-5-2-6-11-17;3-2(4,5)1(6)7/h1-6,8-11,18-19H,7,12-15H2show more

Sinónimos
N2-[2-(2,2-Diphenylethoxy)acetyl]-L-arginine trifluoroacetate | N2-[2-(2,2-diphenylethoxy)acetyl]-L-arginine, 2,2,2-t...
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Lipoteichoic acid from Bacillus subtilis
CAS: 56411-57-5 Fórmula: C₃₉H₇₀N₂O₁₃ Peso molecular: 775

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Nombre IUPAC

[(2S)-1-[(2S,3R,4S,5R,6R)-4-[(2S,3R,4S,5R,6R)-3-acetamido-5-amino-4-hydroxy-6-methyloxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-heptashow more

SMILES

CCCCCCCC=CCCCCCC(=O)OC(COC1C(C(C(C(O1)CO)O)OC2C(C(C(C(O2)C)N)O)NC(=O)C)O)COC(=O)CCCCCC

InChIKey
PANDRCFROUDETH-YLSOAJEOSA-N

InChI

1S/C39H70N2O13/c1-5-7-9-11-12-13-14-15-16-17-18-20-22-31(45)52-28(24-49-30(44)21-19-10-8-6-2)25-50-39-36(48)37(34(46)29(23-42)53-39)54-38-33(41-27(4)4show more
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JR14a
CAS: 2411440-41-8 PubChem CID: 145996525 Fórmula: C₂₅H₂₆Cl₂N₄O₃S Peso molecular: 533.47

≥98%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: J573257
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Nombre IUPAC

(2S)-2-[[5-[bis(4-chlorophenyl)methyl]-3-methylthiophene-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid

SMILES

CC1=C(SC(=C1)C(C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)Cl)C(=O)NC(CCCN=C(N)N)C(=O)O

InChIKey
OHRIKWUZKGNQKQ-IBGZPJMESA-N

InChI

1S/C25H26Cl2N4O3S/c1-14-13-20(21(15-4-8-17(26)9-5-15)16-6-10-18(27)11-7-16)35-22(14)23(32)31-19(24(33)34)3-2-12-30-25(28)29/h4-11,13,19,21H,2-3,12H2,1show more

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Preguntas frecuentes

What can I find under Complement System?

This listing collects compounds associated with Complement System within our Immunology/Inflammation area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.

What should I consider when picking a compound for Complement System?

Consider the reported potency of each Complement System compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.

What quality information is provided for Complement System compounds?

Each Complement System product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

Can I search Complement System compounds by activity or structure?

Yes. Filter the Complement System listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].