m-PEG4-DBCO - ≥98% , CAS No.2228857-36-9

CAS: 2228857-36-9 Cat. No.: M596721 Fórmula: C₂₈H₃₄N₂O₆ Peso molecular: 494.58

CALIDAD & PUREZA ≥98%

Synonyms

m-PEG4-NH-DBCO

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Application

227,228,229

Descripción general

m-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. m-PEG4-NH-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

m-PEG4-DBCO is a DBCO-activated reagents and can react with azides via a copper-free Click Chemistry reaction to form a stable triazole. This reagent can be applied to situations when copper is a concern for DBCO-activated PEGylation.

Especificaciones

Sinónimos

m-PEG4-NH-DBCO

Especificaciones y pureza

≥98%

Condiciones de almacenamiento de almacenamiento

Protected from light,Store at -20°C,Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥98%

Nombres e identificadores

Pubchem Sid

528768700

Sonrisas canónicas

COCCOCCOCCOCCNC(=O)CCC(=O)N1CC2=CC=CC=C2C#CC3=CC=CC=C31

IUPAC Name

4-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-N-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethyl]-4-oxobutanamide

InChIKey

CUEOILOXVJZHLK-UHFFFAOYSA-N

INCHI

1S/C28H34N2O6/c1-33-16-17-35-20-21-36-19-18-34-15-14-29-27(31)12-13-28(32)30-22-25-8-3-2-6-23(25)10-11-24-7-4-5-9-26(24)30/h2-9H,12-22H2,1H3,(H,29,31)

Peso molecular

494.58

Propiedades químicas y físicas

• Sensibilidad: Light sensitive;Moisture sensitive;Heat sensitive
• Peso molecular: 494.600 g/mol
• XLogP3: 1.500
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 15
• Exact Mass: 494.242 Da
• Monoisotopic Mass: 494.242 Da
• Topological Polar Surface Area: 86.300 Ų
• Heavy Atom Count: 36
• Formal Charge: 0
• Complexity: 732.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1