Magnolol - 10mM in DMSO , CAS No.528-43-8

CAS: 528-43-8 Cat. No.: M407956 Fórmula: C₁₈H₁₈O₂ Peso molecular: 266.33 Beilstein Registry Number: 6(4)6918 Número EC: 610-903-7

GRADE & PURITY 10mM in DMSO

Synonyms

NSC 293099 | [1,1'-Biphenyl]-2,2'-diol, 5,5'-di-2-propen-1-yl-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Information

Magnolol Magnolol (NSC 293099) is a bioactive lignin found in the bark of the Houpu magnolia (Magnolia officinalis) which shows antifungal properties. It can block TNF-α-induced NF-KB activation.
In vitro

Magnolol is a bioactive lignin found in the bark of the Houpu magnolia (Magnolia officinalis) which shows antifungal properties. Magnolol preferentially increases (3)H-muscimol binding to hippocampus compared to cortex and cerebellum in vitro. Magnolol has a more potent enhancing effect on GABA_A receptor alpha2 subunit. Magnolol shows significant inhibitory activities against Trichophyton mentagrophytes, Microsporium gypseum, Epidermophyton floccosum, Aspergillus niger, Cryptococcus neoformans, and Candida albicans with minimum inhibitory concentrations (MIC) in a range of 25-100 μg/ml.

In vivo

LD50: Mice 2200mg/kg (i.g.).
Cell Data

cell lines：LNCaP/AR prostate cancer cell line

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Sinónimos

NSC 293099 | [1,1'-Biphenyl]-2,2'-diol, 5,5'-di-2-propen-1-yl-

Especificaciones y pureza

10mM in DMSO

Mecanismos bioquímicos y fisiológicos

Magnolol (NSC 293099) is a bioactive lignin found in the bark of the Houpu magnolia (Magnolia officinalis) which shows antifungal properties. It can block TNF-α-induced NF-KB activation.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nombres e identificadores

• Isómeros SMILES: C=CCC1=CC(=C(C=C1)O)C2=C(C=CC(=C2)CC=C)O
• WGK Alemania: 3
• RTECS: DV5105500
• Número ONU: 3077
• Peso molecular: 266.33
• Beilstein: 6(4)6918
• Reaxy-Rn: 1982224
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1982224&ln=

Propiedades químicas y físicas

• Solubilidad: Solubility (25°C) In vitro DMSO: 100 mg/mL (148.9 mM); Ethanol: 4 mg/mL (5.95 mM); Water: Insoluble
• Punto de ebullición (°C): 180 °C/1 mmHg
• Punto de fusión (°C): 101 °C

Preguntas frecuentes

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 528-43-8, the molecular formula is C18H18O2, and the molecular weight is 266.33 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.