Methylthiouracil - 10mM in DMSO , CAS No.56-04-2

CAS: 56-04-2 Cat. No.: M408545 Fórmula: C₅H₆N₂OS Peso molecular: 142.18 Número EC: 200-252-3

CALIDAD & PUREZA 10mM in DMSO

Synonyms

NSC-193526, NSC-9378 | 6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Information

Methylthiouracil (NSC-193526, NSC-9378) is an antithyroid agent. Methylthiouracil suppresses the productionTNF-αandIL-6, and the activation ofNF-κBandERK1/2.
In vitro

Methylthiouracil acts to decrease the formation of stored thyroid hormone, as thyroglobulin in the thyroid gland. Methylthiouracil is also used in combination with radioactive iodine.

In vivo

Cell Data

cell lines：MM1.S, MM.1R, LR5, RPMI 8226, DOX40, OPM1, OPM2, INA6, and U266

Concentrations：

Incubation Time：

Powder Purity:≥99%

Especificaciones

Sinónimos

NSC-193526, NSC-9378 | 6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one

Especificaciones y pureza

10mM in DMSO

Mecanismos bioquímicos y fisiológicos

Methylthiouracil (NSC-193526, NSC-9378) is an antithyroid agent. Methylthiouracil suppresses the production TNF-α and IL-6, and the activation of NF-κB and ERK1/2.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nombres e identificadores

Isómeros SMILES

CC1=CC(=O)NC(=S)N1

Número ONU

3077

Grupo de embalaje

III

Peso molecular

142.18

Reaxy-Rn

115648

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=115648&ln=

Propiedades químicas y físicas

• Solubilidad: Solubility (25°C) In vitro DMSO: 64 mg/mL (199.17 mM); Water: Insoluble; Ethanol: Insoluble
• Punto de fusión (°C): 330°C