MF-094 - 10mM in DMSO , CAS No.2241025-68-1

CAS: 2241025-68-1 Cat. No.: M655233 Molecular Weight: 535.70 PubChem CID: 138319686

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

MF-094 is a potent and selective USP30 inhibitor with an IC 50 of 120 nM. MF-094 increases protein ubiquitination and accelerates mitophagy

In Vitro

MF-094 has <30% inhibitory activity for a panel of 22 USPs assays at 10 uM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:IC50: 120 nM (USP30)

Specifications

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

MF-094 is a potent and selective USP30 inhibitor with an IC 50 of 120 nM. MF-094 increases protein ubiquitination and accelerates mitophagy.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Names and Identifiers

• Isomeric SMILES: CC(C)(C)NS(=O)(=O)C1=CC=CC2=C1C=CC=C2NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)C4CCCCC4
• PubChem CID: 138319686
• MeSH Entry Terms: MF-094;N-((2S)-1-((5-(tert-butylsulfamoyl)naphthalen-1-yl)amino)-1-oxo-3-phenylpropan-2-yl)cyclohexanecarboxamide
• Molecular Weight: 535.70

Associated Targets(Human)

USP30 Tchem Ubiquitin carboxyl-terminal hydrolase 30 (3 Activities)

Discover Target: USP30

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)