MFZ 10-7 - Moligand™, ≥98% , CAS No.1224431-15-5

CAS: 1224431-15-5 Cat. No.: M650237 Fórmula: C₁₅H₉FN₂ Peso molecular: 236.24

GRADE & PURITY Moligand™, ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

MFZ 10-7 is a highly potent and selective mGluR5 NAM (negative allosteric modulator), with a K i of 0.67 nM for rat mGluR5

In Vitro

MFZ 10-7 has approximately 1150- and 3000-fold lower affinity for MAO-B (monoamine oxidase-B enzyme) and TXA2 (thromboxane A2 receptor), respectively, compared to mGluR5. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

MFZ 10-7 can lower oral sucrose self-administration rate but has no effect on total sucrose intake . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:rat mGluR5 0.67 nM (Ki)

Specifications

Especificaciones y pureza

Moligand™, ≥98%

Mecanismos bioquímicos y fisiológicos

MFZ 10-7 is a highly potent and selective mGluR5 NAM (negative allosteric modulator), with a K i of 0.67 nM for rat mGluR5.

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

ANTAGONIST

Pureza

≥98%

Nombres e identificadores

• Peso molecular: 236.24

Propiedades químicas y físicas

• Solubilidad: DMSO : 17.86 mg/mL (75.60 mM; ultrasonic and warming and heat to 60°C)

Preguntas frecuentes

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1224431-15-5, the molecular formula is C15H9FN2, and the molecular weight is 236.24 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.