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MK-0159 - ≥99% , CAS No.2641484-61-7
AVAILABLE TO ORDER
GRADE & PURITY ≥99%
Storage
Store at 2-8°C,Protected from light,Desiccated
Shipped In
Wet ice
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Why this grade
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at 2-8°C,Protected from light,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
MK-0159 (compound 37) is an orally active, potent and selective CD38 inhibitor, with IC 50 values of 22, 3, and 70 nM for human, mouse and rat CD38 , respectively. MK-0159 also shows good microsomal stability for human and rodent liver microsomes. MK-0159 increases NAD + (nicotinamide adenine dinucleotide) and reduces ADPR (adenosine diphosphate ribose) in whole blood and heart
Form:Solid
IC50& Target:IC 50 : 3 nM (mouse CD38), 22 ± 5 nM (hCD38), 70 nM (rat CD38)
Specifications
Specifications & Purity
≥99%
Biochemical and Physiological Mechanisms
MK-0159 (compound 37) is an orally active, potent and selective CD38 inhibitor, with IC 50 values of 22, 3, and 70 nM for human, mouse and rat CD38 , respectively. MK-0159 also shows good microsomal stability for human and rodent liver microsomes. MK-0159
Storage
Store at 2-8°C, Protected from light, Desiccated
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Purity
≥99%
Names and Identifiers
| Molecular Weight | 400.49 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
| Solubility | DMSO : 100 mg/mL (249.69 mM; Need ultrasonic) |
|---|
Solution Calculators
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Customer Reviews
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