ML161 (Parmodulin 2) - 10mM in DMSO , CAS No.423735-93-7

CAS: 423735-93-7 Cat. No.: M408640 Fórmula: C₁₇H₁₇BrN₂O₂ Peso molecular: 361.23 Número EC: 803-969-5

GRADE & PURITY 10mM in DMSO

Synonyms

Benzamide, 2-bromo-N-[3-[(1-oxobutyl)amino]phenyl]-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Information

ML161 (Parmodulin 2) ML161 (Parmodulin 2) is an allosteric inhibitor of PAR1 with IC50 of 0.26 μM.
In vitro

ML-161 is an allosteric inhibitor of PAR1. ML-161 displays dose-dependent inhibition of thrombin-induced platelet activation, as measured by P-selectin expression. ML-161 displays selective inhibition of SFLLRN and thrombin-induced platelet aggregation, both of which operate via PAR1, and has no effect on AYPGKF, thromboxane, or ADP-induced platelet aggregation, which are all agonists at alternative platelet GPCRs.

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Sinónimos

Benzamide, 2-bromo-N-[3-[(1-oxobutyl)amino]phenyl]-

Especificaciones y pureza

10mM in DMSO

Mecanismos bioquímicos y fisiológicos

ML161 (Parmodulin 2) is an allosteric inhibitor of PAR1 with IC50 of 0.26 μM.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Nombres e identificadores

• Isómeros SMILES: CCCC(=O)NC1=CC(=CC=C1)NC(=O)C2=CC=CC=C2Br
• WGK Alemania: 3
• Peso molecular: 361.23
• Reaxy-Rn: 22413221
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=22413221&ln=

Preguntas frecuentes

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 423735-93-7, the molecular formula is C17H17BrN2O2, and the molecular weight is 361.23 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.