ML252 - ≥99% , CAS No.1392494-64-2

CAS: 1392494-64-2 Cat. No.: M1438161 Fórmula: C₂₀H₂₅ClN₂O Peso molecular: 344.9 PubChem CID: 53393831

GRADE & PURITY ≥99%

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Descripción general

ML252 is a selective inhibitor of KCNQ2 (Kv7.2) channel with an IC 50 s of 69 nM, 2.92 μM, 0.12 μM and 0.20 μM for KCNQ2, KCNQ1 (Kv7.1), KCNQ2/Q3 and KCNQ4, respectively. ML252 also inhibits Cytochrome P450 with IC 50 s of 6.1 nM ( CYP1A2 ), 18.9 nM ( CYP2C9 ), 3.9 nM ( CYP3A4 ), 19.9 nM ( CYP2D6 ), respectively. ML252 shows highly brain penetrant.

Specifications

Especificaciones y pureza

≥99%

Condiciones de almacenamiento de almacenamiento

Protected from light,Store at -20°C,Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Pureza

≥99%

Nombres e identificadores

• Sonrisas canónicas: CCC(C1=CC=CC=C1)C(=O)NC2=CC=CC=C2N3CCCC3.Cl
• IUPAC Name: (2S)-2-phenyl-N-(2-pyrrolidin-1-ylphenyl)butanamide;hydrochloride
• InChIKey: XBYCQOZNTLUEDX-LMOVPXPDSA-N
• INCHI: 1S/C20H24N2O.ClH/c1-2-17(16-10-4-3-5-11-16)20(23)21-18-12-6-7-13-19(18)22-14-8-9-15-22;/h3-7,10-13,17H,2,8-9,14-15H2,1H3,(H,21,23);1H/t17-;/m0./s1
• Isómeros SMILES: CC[C@@H](C1=CC=CC=C1)C(=O)NC2=CC=CC=C2N3CCCC3.Cl
• WGK Alemania: 3
• PubChem CID: 53393831
• Peso molecular: 344.9

Preguntas frecuentes

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C, protected from light, under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1392494-64-2, the molecular formula is C20H25ClN2O, and the molecular weight is 344.9 g/mol. InChIKey XBYCQOZNTLUEDX-LMOVPXPDSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.