Nafadotride - Moligand™, ≥99% , Agonist of 5-HT 1A receptor;Antagonist of D 2 receptor;Antagonist of D 3 receptor;Antagonist of D 4 receptor, CAS No.149649-22-9, Agonist of 5-HT 1A receptor;Antagonist of D 2 receptor;Antagonist of D 3 receptor;Antagonist of D 4 receptor
Nafadotride - Moligand™, ≥99% , Agonist of 5-HT 1A receptor;Antagonist of D 2 receptor;Antagonist of D 3 receptor;Antagonist of D 4 receptor, CAS No.149649-22-9, Agonist of 5-HT 1A receptor;Antagonist of D 2 receptor;Antagonist of D 3 receptor;Antagonist of D 4 receptor
CALIDAD & PUREZAMoligand™?Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.≥99%
Potent, selective D 3 antagonist (K i values are 0.52 nM (D 3 ), 269 nM (D 4 ) and 5 nM (D 2 )).
Condiciones de almacenamiento de almacenamiento
Room temperature,Desiccated
Enviado en
Normal
Grado
Moligand™
Tipo de acción
AGONIST, ANTAGONIST
Mecanismo de acción
Agonist of 5-HT 1A receptor;Antagonist of D 2 receptor;Antagonist of D 3 receptor;Antagonist of D 4 receptor
Nota
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This compound belongs to the class of organic compounds known as naphthalenecarboxamides. These are compounds containing a naphthalene moiety, which bears a carboxylic acid amide group at one or more positions. Naphthalene is a bicyclic compound that is made up of two fused benzene rings.
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
Solubilidad
Soluble in 1eq. HCl to 50 mM
Peso molecular
365.500 g/mol
XLogP3
4.000
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
7
Exact Mass
365.21 Da
Monoisotopic Mass
365.21 Da
Topological Polar Surface Area
65.400 Ų
Heavy Atom Count
27
Formal Charge
0
Complexity
543.000
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
1
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
The total count of all stereochemical bonds
0
Covalently-Bonded Unit Count
1
Calculadoras de soluciones
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