NF 157 - ≥90% , CAS No.104869-26-3

CAS: 104869-26-3 Cat. No.: N288559 Molecular Weight: 1437.08 PubChem CID: 71433548

GRADE & PURITY ≥90%

Synonyms

NF 157 | AKOS024457107 | Hexasodium;8-[[4-fluoro-3-[[3-[[3-[[2-fluoro-5-[(8-oxidoperoxysulfanyl-4,6-disulfonatonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl]phenyl]carbamoylamino]benzoyl]amino]benzoyl]amino]naphthalene-1,3,5-trisulfonate | AKOS025294016 | J-

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Specifications

Synonyms

NF 157 | AKOS024457107 | Hexasodium;8-[[4-fluoro-3-[[3-[[3-[[2-fluoro-5-[(8-oxidoperoxysulfanyl-4, 6-disulfonatonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl]phenyl]carbamoylamino]benzoyl]amino]benzoyl]amino]naphthalene-1, 3, 5-trisulfonate | AKOS025294016 | J-

Specifications & Purity

≥90%

Biochemical and Physiological Mechanisms

Purinergic receptor antagonist that potently inhibits P2Y11receptor activity (IC50= 463 nM). Displays selectivity for P2Y11and P2X1receptors over P2Y1, P2Y2, P2X2, P2X3, P2X4and P2X7receptors. Inhibits NAD+-induced activation of human granulocytes.

Storage

Store at -20°C, Desiccated

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

ANTAGONIST

Purity

≥90%

Names and Identifiers

• Canonical Smiles: [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-]OOSC1=C2C(NC(=O)C3=CC(NC(=O)C4=CC(NC(=O)NC5=CC(=CC=C5)C(=O)NC5=CC(=CC=C5F)C(=O)NC5=CC=C(C6=CC(=CC(=C56)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O)=CC=C4)=C(F)C=C3)=CC=C(C2=CC(=C1)S([O-])(=O)=O)S([O-])(=O)=O
• InChIKey: QJFCMJZVZFAWGF-UHFFFAOYSA-H
• Isomeric SMILES: C1=CC(=CC(=C1)NC(=O)NC2=CC=CC(=C2)C(=O)NC3=C(C=CC(=C3)C(=O)NC4=C5C(=CC(=CC5=C(C=C4)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])F)C(=O)NC6=C(C=CC(=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)[O-])S(=O)(=O)[O-])SOO[O-])F.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
• Alternate CAS: 99777-88-5
• PubChem CID: 71433548
• Molecular Weight: 1437.08

Chemical and Physical Properties

• Solubility: Solvent:water, Max Conc. mg/mL: 71.85, Max Conc. mM: 50
• Sensitivity: Hygroscopic